Talking Sleep A Guide to OSA Endotyping
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Nov 22, 2024 Dr. Danny J. Eckert, a leading sleep and respiratory physiologist and director at the Adelaide Institute for Sleep Health, discusses his groundbreaking work on OSA endotyping. He reveals that 70% of OSA patients suffer from non-anatomical causes, stressing the need for tailored treatment approaches. The chat covers innovative methodologies for assessing airway collapse and explores the significant impact of nasal obstruction on sleep quality. Eckert also highlights the potential of non-PAP treatments and new biomarkers for an improved understanding and management of obstructive sleep apnea.
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Simplified Estimation of Pcrit
- Use therapeutic CPAP pressure and apnea-to-hypopnea ratio from sleep studies to estimate airway collapsibility.
- Simple wakefulness tests can also provide estimates but are mainly research tools presently.
Nasal Obstruction's Role in OSA
- Nasal obstruction plays a significant role in sleep apnea by increasing downstream pressure.
- Blocking the nose experimentally can induce sleep apnea in healthy subjects.
Snoring Trauma Impairs Airway Muscles
- Chronic snoring may cause trauma or neuropathy to the nerves controlling airway muscles.
- This could impair muscle function and contribute to sleep apnea.
