Dr. Anurag Singh, CMO of Timeline, discusses Urolithin A's impact on mitochondrial health, muscle strength, and inflammation. They explore mitophagy, synergistic effects with ketones, and transdermal delivery systems. Urolithin A's potential in combatting age-related decline and future applications is also highlighted.
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question_answer ANECDOTE
From Clinician To Nutrition Researcher
Anurag Singh described his path from medical training in India to research in the US and a PhD in immunology.
His early work with naturopaths and bromelain sparked his interest in nutrition research.
insights INSIGHT
Deconstructing Wonder Foods Reveals Active Molecules
Researchers deconstructed pomegranate polyphenols to find the single active metabolite driving benefits.
Urolithin A emerged as the key molecule among hundreds of bioactives in pomegranate.
insights INSIGHT
Microbiome Controls Urolithin A Production
Gut microbiome determines whether dietary ellagic acid is converted into urolithin A.
Only ~12% of North Americans can produce meaningful circulating urolithin A after pomegranate intake.
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Join us in this enlightening episode as we dive deep into the emerging research behind Urolithin A and its impact on mitochondrial health with Dr. Anurag Singh, a leading expert in the field and the Chief Medical Officer of Timeline.
The discussion spans various facets of Urolithin A, from its origin in pomegranates and other foods to its potential in improving mitochondrial health, muscle strength, and reducing inflammation. Dr. Singh shares insights from his decade-long research on this remarkable compound, discussing everything from the science of mitophagy to its implications for overall health. You’ll also hear about the synergistic effects of combining Urolithin A with other mitochondrial-targeting compounds and therapies like ketogenic diets and exogenous ketones.
The episode also reveals fascinating findings on how Urolithin A interacts with our cellular machinery to combat age-related decline and offers a peek into future applications, including a unique perspective on transdermal delivery systems. Dr. Singh’s expert knowledge sheds light on the exciting future directions of Urolithin A research and its vast potential applications.
About Dr. Anurag Singh: Dr. Anurag Singh is currently the Chief Medical Officer at Timeline, a company that develops next-generation advanced nutritional products targeting improvements in mitochondrial and muscle health. With an M.D. in internal medicine and a Ph.D. in immunology, his experience includes work for top consumer health and startup/biotech companies. He’s authored more than 40 articles in top science journals and has designed and led more than 50 randomized clinical trials in nutrition.
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