The Dr. Tyna Show

Peptides to Support Your GLP1 Journey | Kyal Van Der Leest of LVLUP

Oct 31, 2025
Kyal Van Der Leest, the brains behind LVLUP, dives deep into the world of peptides and GLP-1s. He shares essential strategies for supporting gut and liver health while using GLP-1s, highlighting the risks of muscle loss and the importance of preventive measures. Discover how microdosing differs from standard dosing, and why cycling peptides is crucial for effectiveness. Kyal also discusses the role of key supplements in hormone balance and longevity pathways. Tune in for practical tips to enhance performance and health while navigating these powerful therapies.
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ADVICE

Fix The Gut Before GLP‑1s

  • Heal and stabilize your gut before starting any GLP‑1 therapy, even microdoses.
  • Treat SIBO, leaky gut, and bile issues proactively to avoid downstream metabolic and inflammatory problems.
INSIGHT

GLP‑1s Slow Motility, Raise SIBO Risk

  • Slowed gastric motility from GLP‑1s can cause SIBO and bile stasis, worsening digestion.
  • Supporting bile flow (e.g., TUDCA, ox bile) helps clear bacteria and improve fat absorption.
ADVICE

Protect Liver During Rapid Weight Loss

  • Use binders and liver support when losing weight rapidly to prevent toxin redistribution.
  • Take binders at bedtime and away from other supplements to aid clearance.
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