Good Life Project Future of Medicine: The Science of Super-Aging [Ep. 1]
Nov 3, 2025
Dr. Eric Topol, a leading cardiologist and researcher, delves into groundbreaking approaches to longevity and disease prevention. He discusses the concept of 'super agers' and how AI-powered diagnostics can forecast health outcomes years ahead. Topol explains the importance of early detection, the role of inflammation in aging, and practical lifestyle interventions like diet and exercise. He also highlights innovative treatments, including the impact of GLP-1 drugs on inflammation and brain health, emphasizing personalized strategies for a healthier future.
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Most Older Adults Have Chronic Disease
- 80–85% of people 65+ have at least one chronic disease, showing current aging is unhealthy at scale.
- Superagers avoid cancer, neurodegeneration, and cardiovascular disease into their 80s and 90s.
Organ Clocks Reveal Hidden Aging
- Organ clocks measure the pace of aging for specific organs using blood protein profiles.
- These clocks can reveal accelerated organ aging decades before symptoms appear.
AI Can Predict 20-Year Health Trajectories
- AI models using records and self-reports can predict a person's health outcomes up to 20 years ahead.
- These predictions get far more powerful when combined with organ clocks, proteins, and genetics.
