Wisdom Wednesday - Anti-aging strategies part 4 - Combatting 'Inflammaging'
Feb 4, 2025
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Discover the intriguing concept of 'Inflammaging,' highlighting its role in chronic inflammation as we age. Learn about its connections to age-related diseases and explore actionable strategies to combat this condition. The discussion includes lifestyle changes and essential supplements that can promote healthier aging. Tune in for practical tips to enhance your well-being and potentially extend your lifespan!
Inflammaging is a chronic low-grade inflammation linked to age-related diseases, influenced by immune system changes and gut health.
Implementing lifestyle interventions like exercise and an anti-inflammatory diet can effectively combat chronic inflammation and promote better health.
Deep dives
Understanding Inflammaging
Inflammaging refers to the chronic low-grade inflammation that develops as we age, which differs significantly from acute inflammation that helps the body recover from infections and injuries. This persistent inflammation is linked to several age-related diseases, including heart disease, diabetes, and even dementia. Factors contributing to inflammaging include immune system degeneration, changes in gut microbiota, and increased oxidative stress. Over time, chronic inflammation can damage healthy cells and tissues, leading to a decline in overall health and increased susceptibility to diseases.
Major Contributors to Inflammation
Key contributors to chronic inflammation include dysregulation of the immune system, which can lead to an overactive innate immune response and a weakened adaptive immune response. Changes in gut microbiota, often due to poor dietary choices, can result in leaky gut syndrome, allowing harmful particles to enter the bloodstream and trigger an inflammatory response. Additionally, the accumulation of senescent cells—cells that refuse to die—can secrete inflammatory molecules, perpetuating a cycle of inflammation. An excess of processed foods can lead to metaflammation, a form of chronic inflammation resulting from poor nutrition and calorie overload.
Strategies to Combat Inflammation
Lifestyle interventions play a crucial role in combating chronic inflammation, with exercise being one of the most effective methods. Regular physical activity releases myokines and anti-inflammatory cytokines that can reduce levels of inflammatory markers in the body. Dietary changes, such as adopting an anti-inflammatory Mediterranean diet rich in omega-3 fatty acids and avoiding ultra-processed foods, can significantly lower inflammation levels. Additionally, incorporating quality supplements like omega-3s, curcumin, Glynac, and vitamin D can further help manage inflammation and support overall health.
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Combatting Inflammaging: Strategies for Healthy Aging