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TMHS 805 - How Your Environment Can Cause Dementia & Cognitive Decline - With Max Lugavere

The Model Health Show

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Heritability and Environmental Factors in Neurodegenerative Diseases

Neurodegenerative conditions like Alzheimer's and Parkinson's diseases have a low heritability, with the environment playing a significant role. Genetic risk factors for Alzheimer's are not deterministic, and only a small percentage of cases are hereditary. Parkinson's is also suggested to be primarily environmentally mediated. The Lancet Commission on Dementia in 2020 highlighted 12 modifiable and three non-modifiable risk factors for these conditions.

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