Gut Microbiome Disruptions and Histamine Intolerance

Disruptions in the gut microbiome, such as bacterial overgrowth, can lead to histamine intolerance by consuming the D-A-O enzyme needed to degrade histamine. Symptoms like bloating, constipation, and diarrhea are common indications. Small Intestinal Bacterial Overgrowth (SIBO) can damage important enzymes on the intestinal lining, impacting food digestion. Histamine-producing bacteria can further exacerbate histamine intolerance, making stool tests crucial for diagnosis.