242. Debunking Cholesterol Myths: New Study Reveals Surprising Findings! With Dave Feldman
Paul Saladino MD podcast
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Macrophages and Atherosclerosis
Macrophages are vital immune cells present in the sub-entimal space that work to clear away debris, including oxidized LDL particles trapped in proteoglycans. In atherosclerosis, macrophages act as emergency workers by consuming debris such as necrotic macrophages. The present lipid hypothesis suggests that when macrophages encounter oxidized LDL particles, they consume them but get stuck, contributing to the progression of atherosclerosis.
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