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Dr. Mark D'Esposito: How to Optimize Cognitive Function & Brain Health

Huberman Lab

NOTE

The Link Between Estrogen and Dopamine Levels/working memory in Cognition

Estrogen receptors in the frontal lobes affect dopamine levels, impacting working memory. Higher estrogen levels correlate with increased dopamine levels, leading to improved working memory. Anecdotal evidence suggests estrogen supplements can enhance working memory in post-menopausal women. Research shows a clear connection between estrogen levels, dopamine, frontal lobe function, and working memory. Hormones, especially estrogen, play a crucial role in cognition and vascular function for both men and women. Optimal estrogen levels are essential for cognitive and vascular health, debunking the misconception of testosterone being the sole important hormone. Estrogen boosts dopamine activity, increasing the availability of dopamine in the brain. Fluctuations in estrogen levels during the menstrual cycle and across individuals can significantly impact cognitive functions, emphasizing the importance of understanding individual hormone levels for cognitive health.

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