ACQ2 by Acquired cover image

The Scientific Journey Behind Ozempic (with Lotte Bjerre Knudsen, Novo Nordisk's Chief Scientific Advisor)

ACQ2 by Acquired

00:00

GLP-1's Role in the Body

  • GLP-1 is one of many hormones and neuromodulators that help process food after eating.
  • It's not as essential as insulin, which is crucial for survival in type 1 diabetes.
  • The fact that GLP-1 isn't super important allows it to be used pharmacologically in higher amounts and for extended durations.
  • This works because there's no strong counterregulation, unlike other more critical substances.
  • While it is hard to prove experimentally, GLP-1 likely gets into the brain and some GLP-1 is produced there.
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