Invest Like the Best with Patrick O'Shaughnessy cover image

Alex Telford - Unlocking Innovation in Pharma - [Invest Like the Best, EP.360]

Invest Like the Best with Patrick O'Shaughnessy

NOTE

Accuracy and Limitations of Alpha Fold for Drug Discovery

Alpha Fold can serve as a useful starting point for drug discovery, but it has limitations in making accurate predictions for the configuration of drug-binding sites. Improving Alpha Fold requires more data, which is time-consuming to collect. Alpha Fold is trained on decades of protein structures, which has accelerated parts of the process but not the overall drug discovery. The impact of Alpha Fold on the pharmaceutical industry is expected to be gradual, with its tools being useful yet requiring time to deploy and integrate effectively. Contrary to popular belief, the rate limitation in drug discovery is more related to downstream clinical development and testing, rather than the ability to design new molecules and drugs.

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