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Dr. Casey Means: Transform Your Health by Improving Metabolism, Hormone & Blood Sugar Regulation
Huberman Lab
**reduce cravings - satiety **
The body possesses nutrient sensor cells, particularly L cells in the gut, which when adequately stimulated, trigger the release of satiety hormones like GLP1, effectively reducing hunger and cravings. To optimize this process, it's essential to consume whole foods that nourish these cells, unlike processed foods that fail to stimulate satiety effectively. Furthermore, strategies exist to enhance GLP1 production. These include increasing the number of L cells, promoting their hormone production, and inhibiting the enzyme DPP4, which degrades GLP1. Short-chain fatty acids, derived from dietary fiber fermentation, play a critical role in promoting the growth of L cells, suggesting that a high-fiber diet is beneficial for gut health and satiety hormone production. Emphasizing fiber intake is crucial not only for enhancing GLP1 levels but also for overall well-being and reducing dependency on pharmaceutical solutions in managing appetite and cravings.
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