Creatine has been shown to have benefits on muscle performance when combined with exercise. However, when it comes to bone health, it is only effective when combined with resistance training or physical activity over a longer period of time. Interestingly, creatine also seems to have some brain benefits, although more research is needed in this area. As for taking creatine during a calorie deficit, it may help offset muscle loss and has anti-catabolic effects. While there is no empirical evidence, it is worth considering for its potential in maintaining strength.

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