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#179 – Randy Nesse on why evolution left us so vulnerable to depression and anxiety

80,000 Hours Podcast

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Balancing False Positives in Response to Threats

The brain strives to maintain an appropriate level of false positives in response to threats. The frequency of panic or anxious responses depends on the likelihood of an actual threat. If a threat is improbable, there is no need for frequent panic or anxiety. Conversely, if a threat is common, a heightened state of alertness is warranted. Panic disorder can be created by amplifying a single panic attack through medical reassurance that might increase false positives, leading to persistent anxiety and panic.

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