Berberine, an herb similar to metformin in promoting longevity and managing blood sugar levels, poses significant health risks, particularly concerning heart rate regulation. While it shows potential advantages, such as those associated with metabolic health, there are alarming reports of individuals experiencing dangerously low heart rates, notably during stressful situations. Instances of heart lock have been documented in emergency reports linked to berberine use. Caution is warranted, as personal experiences underscore the potential for severe adverse effects, challenging any perceived benefits of this supplement.

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