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250. When You Should Worry About LDL Cholesterol with Mike Fave

Paul Saladino MD podcast

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Questioning the Vestigial Nature of LDL and APO-B Proteins

Some experts suggest that LDL and APO -B proteins may be vestigial remnants from our evolutionary past, once used to combat infections. However, with modern antibiotics, the necessity of these proteins is debated. Lowering LDL levels can have potential downsides, but studies show that LDL-C is not associated with cardiovascular disease in individuals with a negative coronary artery calcium score.

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