4min snip

The Tim Ferriss Show cover image

#605: Hamilton Morris and Dr. Mark Plotkin — Exploring the History of Psychoactive Substances, Synthetic vs. Natural Options, Microdosing, 5-MeO-DMT, The “Drunken Monkey” Hypothesis, Timothy Leary’s Legacy, and More

The Tim Ferriss Show

NOTE

The Placebo Effect in Psychedelic Experiences

Alexander Shulgan, also known as Sasha, was in the navy and injured his thumb, requiring a small surgical procedure. After being given orange juice with sugar crystals, he believed it was morphine and experienced a placebo effect. As a scientist who synthesized unknown substances, he was aware of the power of placebos and the nocebo effect. The lesson is to be skeptical, scrutinize experiences and conduct work in an evidence-based manner. Claims about substances must be backed up with research to avoid ecological consequences.

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