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36. Jalal Khan: Circadian Biology, Mitochondria, POMC and Why You Need Sunlight for Optimal Health
Regenerative Health with Max Gulhane, MD
The Role of Light and POMC in Circadian Rhythm and Hormone Regulation
Light influences the activity of the polypeptide POMC throughout the day, creating different proteins based on the sunlight's composition. In the morning, blue light triggers the production of ACTH from POMC, stimulating cortisol release to wake us up. As the day progresses, UV light suppresses cortisol production, illustrating the intricate dance between different light frequencies in regulating hormone levels. Leptin's role in this process remains to be explored.
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