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More Plates More Dates cover image

The Bryan Johnson Podcast

More Plates More Dates

NOTE

Understand the Impact of Dietary Fats and Timing on Drug Absorption

A high-fat diet significantly enhances drug absorption by 25 to 35 percent, indicating the need to consider dietary fats when evaluating medication effectiveness. This effect also extends to basic vitamins, which can be inhibited by other substances. The conversation highlights the continued use of metformin in anti-aging treatments despite mixed evidence regarding its efficacy. Additionally, there is mention of 17 alpha estradiol, known for its benign effects, and the potential future impact of full statin gene therapy, which demonstrates a considerable effect size in anti-aging applications.

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