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The Peter Attia Drive cover image

#272 ‒ Rapamycin: potential longevity benefits, surge in popularity, unanswered questions, and more | David Sabatini, M.D., Ph.D. and Matt Kaeberlein, Ph.D.

The Peter Attia Drive

NOTE

The presence of M-torque in different types of cells

M-torque and M-torque one are present in virtually all types of cells, including red blood cells and platelets. The protein M-torque one is considered critical for the health of almost every cell. Rapamycin, an allosteric inhibitor, affects M-torque by preventing certain substrates from reaching its kinase domain. This inhibition analogy is explained as blocking the entrance to a cave with a boulder without fully obstructing it.

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