Discussion on RSV Vaccines, Pregnancy Approval, and a Novel Antidepressant

RSV vaccines have been discussed with trials focusing on older patients. Currently, only the Pfizer vaccine is approved for pregnant women in the third trimester, while the GSK vaccine is not approved due to an increased risk of miscarriage. On the other hand, a novel antidepressant called Jeparone, a 5-HT1A partial agonist, recently received FDA approval after being rejected three times. It is considered an option for patients who cannot tolerate SSRIs, with reported side effects of dizziness and nausea but no weight gain, fatigue, or sexual side effects. There is anticipation for potential off-label use of Jeparone for sexual dysfunction, with or without depression.