The Curbsiders Internal Medicine Podcast cover image

The Curbsiders Internal Medicine Podcast

#437 Clinical Pearls ACP #IM2024

Apr 29, 2024
Topics covered include angina, COPD-asthma overlap, home oxygen, colon cancer screening, cancer survivorship, tobacco cessation, e-cigarettes, new drugs, RSV vaccine, addiction medicine, interstitial lung disease, APOL1-mediated kidney disease, testosterone therapy, and antimicrobial resistance.
57:32

Podcast summary created with Snipd AI

Quick takeaways

  • Veneprasan and Fezilinitant offer new treatment options for severe GERD and menopausal symptoms respectively.
  • Cannabis use has both benefits for sleep regulation and risks of adverse cardiovascular effects, emphasizing careful consideration.

Deep dives

Update on Novel Medications: GERD Treatment and Menopausal Symptoms

One of the recent FDA-approved medications discussed in the podcast was Veneprasan, a potassium competitive acid blocker used for refractory GERD. It showed efficacy in severe erosive esophagitis. Another medication, Fezilinitant, a neurokinin receptor blocker, was highlighted for menopausal symptom treatment due to its effectiveness in reducing hot flashes. The session also covered RSV vaccines, with Moderna developing an mRNA vaccine. The fourth FDA-approved drug, Jeparone, a 5-HT1A partial agonist, offers a potential alternative for depression treatment without weight gain or sexual side effects.

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