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Medical Interventions (TRT, HGH, Stem Cells, Peptides, etc.) For Longevity | Episode 5
Lifespan with Dr. David Sinclair
Understanding the Impact of Exozomes on Aging and Health
Research has shown that inflammation and damage to the hypothalamus, a small organ in the brain, can impact the overall health and aging process of an animal. Neuronal stem cells in the hypothalamus secrete exozomes that signal the body to survive, potentially leading to a longer lifespan when extracted and administered to mice. Conversely, deleting these specialized cells results in accelerated aging and diseases, emphasizing the critical role of exozomes. While the specific component responsible for these effects remains unclear due to the complexity of exozomes, isolating and replicating it could lead to drug development in the future. Additionally, recent studies have demonstrated the rejuvenating effect of exozome replacement on senescent cells, offering promising possibilities for treating conditions like ulcer healing and addressing cellular aging.
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