Lifespan with Dr. David Sinclair

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Medical Interventions (TRT, HGH, Stem Cells, Peptides, etc.) For Longevity | Episode 5

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Feb 2, 2022

Guest

David Sinclair

58:55

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INSIGHT

Adversity vs. Abundance

Feeling younger doesn't equal reversed biological aging.
Adversity mimetics, like exercise and intermittent fasting, signal the body to hunker down.

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ADVICE

Boost Hormones Naturally

Try natural methods to boost testosterone and growth hormone first.
Exercise, specifically targeting large muscle groups, can increase testosterone naturally.

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INSIGHT

Peptides and Cellular Communication

Peptides, like hormones, are amino acid strings used for cell communication.
Some peptides promote longevity by mimicking adversity, while others signal abundance.

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The All in One Daily Drink to Support Better Health and Performance

01:57 • 4min

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Testostrone Replacement

05:29 • 2min

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Testostron Is Good for Longevity

07:06 • 2min

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Is Itosos Test Oseron a Good Thing?

What Are the Best Anti Aging Supplements?

13:17 • 2min

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Insolen and Its Health Benefits

Are Peptides Safe for Aging?

19:05 • 2min

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Is This Scientifically Validated?

20:57 • 3min

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Xsoms and Peptides and Anti-Aging

24:11 • 2min

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Exozomes in the Body of a Mouse

26:26 • 2min

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Can Exisoms Rejuvenate Sanescence Cells?

28:33 • 2min

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Exsoms Are a Potential Therapy for Longevity

Is It Possible to Turn a Cell Into a Cell?

33:29 • 2min

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Is There a Problem With Pluripotent Cells Right?

35:40 • 2min

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Stem Cells Aren't Just for Hair Loss

37:30 • 2min

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How to Bank Stem Cells in Adults

39:30 • 2min

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The Potential of Stem Cells to Treat Aging

41:43 • 2min

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Is Stem Cells a Good Anti Aging Solution?

43:42 • 2min

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How to Reverse the Age of Cells and Tissues in a Mouse?

45:38 • 2min

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How to Restore Eyesight in Mice

47:31 • 2min

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Is There a Universal Mechanism of Age Resetting?

49:05 • 3min

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Met Foreman Is a Good Anti Aging Treatment

51:35 • 2min

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Is Growth Ormon a Long Term Anti Aging Treatment?

53:19 • 2min

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Is This Really Reversing Aging?

54:56 • 2min

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Stay Young, Stay Alive, Stay Young

57:20 • 2min

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In this week’s episode of the Lifespan podcast, Dr. David Sinclair and co-host Matthew LaPlante cover potential anti-aging interventions that are on the cutting edge. They share the latest research surrounding testosterone replacement therapy (TRT), human growth hormone (HGH), peptide supplementation, exosomes, stem cells, and cellular reprogramming. The idea of human rejuvenation and potential paths towards resetting the aging clock is also discussed.

Thank you to our sponsors:

Athletic Greens - https://athleticgreens.com/sinclair
InsideTracker - https://insidetracker.com/sinclair
Levels - https://levels.link/sinclair

Our Patreon page: https://www.patreon.com/davidsinclair

Lifespan book: https://amzn.to/3sUqurT

Dr. David Sinclair Social:

Instagram
Twitter
Facebook

To stay up to date with David's work to democratize biological age testing and insights, visit tallyhealth.com.

Matthew LaPlante's Social:

Twitter

Timestamps:

(00:00:00) Kicking Off Episode Five: Interventions on the Cutting Edge

(00:02:39) Expressing Gratitude to the Sponsors

(00:05:28) Testosterone Replacement Therapy

(00:10:09) Human Growth Hormone

(00:13:56) Peptide Supplementation and Regenerative Signaling

(00:18:11) MOTS-c, Humanin, and Other Peptides

(00:25:05) Exosome Therapy

(00:31:56) A Primer on Stem Cells and Yamanaka Factors

(00:37:59) Stem Cell Aging and Cord Blood Banking

(00:41:42) The Therapeutic Potential of Stem Cells

(00:43:37) Cellular Reprogramming

(00:51:35) Resetting the Aging Clock

(00:56:50) The Future Looks Bright

(00:58:15) Next Week’s Episode: External Aging

(00:58:36) Subscription and Support Options

For the full show notes, including the peer-reviewed studies, visit the Lifespan podcast website.

Please note that Lifespan with Dr. David Sinclair is distinct from Dr. Sinclair's teaching and research roles at Harvard Medical School. The information provided in this show is not medical advice, nor should it be taken or applied as a replacement for medical advice. The Lifespan with Dr. David Sinclair podcast, its employees, guests and affiliates assume no liability for the application of the information discussed.

Special thanks to our research assistants, Adiv Johnson & Sarah Ryan.

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