#133 – Manolis Kellis: Biology of Disease
Lex Fridman Podcast
Understanding Genetic Perturbations: Steps to Finding Target Genes
Understanding genetics can lead to the development of pharmaceutical therapeutics or interventions that affect the expression of genes. The first four steps are figuring out genetics, tissue of action, responsible nucleotides, and motif and upstream regulator. The next two steps are identifying the targets and tracing them to biological processes and genes. This knowledge can help find target genes for therapeutics.
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