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#133 – Manolis Kellis: Biology of Disease

Lex Fridman Podcast

NOTE

The Role of irXtN and irX5 in Thermogenesis and Fat Generation

Thermogenesis is a process that regulates heat and calories in the body, controlled by irXtN and irX5. Some people are unable to turn on thermogenesis due to genetic mutations, which can be a benefit in a food-scarce environment but leads to obesity in a food-abundant one. Mitochondria and lipids play a role in this process.

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