Data gaps exist in understanding the necessity of omega-3 supplementation in plant-exclusive diets. While not deemed absolutely essential, supplementing with DHA and EPA via sources like algae oil can provide a low-risk, beneficial insurance policy. Observational evidence consistently associates fish intake and DHA with reduced risks of cardiovascular and neurodegenerative diseases, as well as lower overall mortality. However, the perceived health benefits of fish may be influenced by the diets of those consuming it, as studies often compare fish eaters to those consuming unhealthy diets high in red or processed meats. This suggests a broader context is needed to evaluate omega-3 needs in plant-exclusive eaters versus those consuming diverse diets.

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