Histamine intoxication, mainly caused by bad fish and occasionally by certain cheeses with high histamine levels, has increased in outbreaks over the past decade, posing a significant global food security issue. Symptoms include throbbing headache, nausea, explosive diarrhea, flushed face, palpitations, and profuse sweating, lasting for about half a day. Histamine intoxication is a one-time event typically linked to consuming contaminated food, like funky tuna. In contrast, histamine intolerance is a chronic condition, leading to more frequent reactions and potentially triggered by ordinary foods.

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