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#133 – Manolis Kellis: Biology of Disease

Lex Fridman Podcast

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Localization of genetic variants associated with different health traits

Genetic variants associated with immune traits are enriched in immune cells. Similarly, type 2 diabetes is associated with pancreatic islets and blood pressure is localized in the left ventricle of the heart. Height is linked to embryonic stem cells while inflammatory bowel disease is associated with both immune and digestive components.

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