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Dr. Mary Claire Haver: How to Navigate Menopause & Perimenopause for Maximum Health & Vitality
Huberman Lab
Hormones and Neurotransmitters in Brain Health During Perimenopaus
The brain and nervous system have abundant hormone receptors, including estrogen, testosterone, androgen receptors, which interact directly with neuromodulators like serotonin, dopamine, epinephrine, acetylcholine, and GABA. Hormones play a significant role in neural development, influencing the expression of neurotransmitters in neurons. The intricate relationship between hormones and neurotransmitters is crucial for various aspects of brain health beyond cognition, including neuron maintenance and limiting neurodegeneration. Hormones are not solely related to the body but also play a critical role in brain function. During perimenopause, women may experience psychological shifts such as increased anxiety, loss of executive functioning, cognitive decline, and difficulty with job-related tasks, leading to significant impacts such as women quitting their jobs due to menopause symptoms.
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