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The Science & Treatment of Obsessive-Compulsive Disorder (OCD)

Huberman Lab

NOTE

Exploring Neurosteroid Levels in OCD Patients including cortisol

The study aimed to investigate neurosteroid levels in individuals with OCD, focusing on cortisol due to its association with stress and anxiety. The research compared hormone levels in 30 OCD patients and 30 healthy controls, revealing significantly elevated cortisol in females with OCD, suggesting a possible link to increased anxiety. In males with OCD, cortisol levels were also higher, while testosterone levels were reduced, which aligns with the competitive relationship between cortisol and testosterone synthesis pathways. The findings provide insights into the potential role of cortisol in anxiety disorders like OCD.

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