Menopause marks the depletion of a woman's egg supply, leading to the cessation of estradiol production by the ovaries. Estradiol, the primary estrogen hormone, plays a crucial role in reducing inflammation and supporting reproductive functions. During perimenopause, the drastic decline in egg quantity and quality results in irregular hormonal fluctuations, impacting the body's functions. Symptoms of perimenopause can manifest 7 to 10 years before the final menstrual period, including joint pain, brain fog, weight gain, and fatigue. Health care providers often overlook these symptoms, leading to misdiagnosis or lack of diagnosis. Hormone tests during perimenopause are often inconclusive due to the fluctuating hormone levels, resulting in unnecessary healthcare costs. A single hormone test doesn't provide an accurate representation of a woman's hormonal status during perimenopause, necessitating continuous monitoring over a period of time.

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