Magnesium supplements, particularly magnesium glycinate, offer significant benefits for brain health due to their high bioavailability and cost-effectiveness. Magnesium glycinate provides additional glycine, which is beneficial for physically active individuals, enhancing the overall value of supplementation. Other forms, like magnesium threonate, are often overhyped, lacking substantial evidence of superiority despite some limited studies. The distinctions in how magnesium forms behave in the gut remain unclear, particularly regarding claims that certain forms increase brain magnesium levels more effectively. Thus, magnesium glycinate remains the preferred choice for effective and economical supplementation.

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