48sec snip

The Proof with Simon Hill cover image

Science of exercise, mitochondrial health and longevity | Biochemist Kieron Rooney

The Proof with Simon Hill

NOTE

The Impact of Movement on mitochondria and AMP accumulation

Movement increases mitochondria production and triggers the release of a molecule called AMP, which activates a protein called AMP kinase. AMP kinase's role is to attach phosphate molecules to other proteins, activating a protein called PGC-one. PGC-one, short for peroxisome proliferator-activated receptor gamma coactivator 1, is involved in promoting mitochondrial biogenesis. So, movement not only burns calories but also stimulates the production of more mitochondria.

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