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Fasting Masterclass

The Proof with Simon Hill

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Caloric and Time Restriction's Effect on Mice Lifespan

Providing mice the same amount of food at nighttime extended their lifespan by 35%. Caloric restriction alone increases lifespan by 10%. Implementing time restriction, whether during the day or night, can further extend lifespan by 10%. Aligning time restriction with the cicadian cycle can offer an additional 15% benefit. Human experiments showed that mice with calorie restriction, regardless of the time of day, had similar outcomes in terms of body weight, muscle mass, fat mass, and insulin levels.

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