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Episode #275: Rest Periods

Barbell Medicine Podcast

NOTE

Phosphocreatine as the primary molecule in replenishing energy during exercise

Energy in human activity is predominantly derived from ATP and phosphocreatine, where ATP breakdown leads to muscle contraction. Despite the small decrease in ATP levels during exercise, studies show quick regeneration happening during the exercise itself, requiring only about 3 to 5 minutes post-exercise for ATP stores to reach their maximum. Rather than ATP, phosphocreatine (PCR) is highlighted as the key molecule due to its higher muscle levels and the efficiency of creatine kinase in breaking it down compared to ATP.

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