Recognize Patterns, Expand Diagnoses

A risk score for ATTR cardiomyopathy highlights crucial clinical factors including age, gender, hypertension, and wall thickness that help in assessing suspicion for the condition. Older age and male gender increase risk, while hypertension complicates the interpretation of thickened heart walls, emphasizing the need for cautious differential diagnosis. It is vital to differentiate between true hypertrophy and wall thickness due to infiltration as mislabeling left ventricular hypertrophy can limit diagnostic possibilities. Increased left ventricular wall thickness should prompt further investigation to identify the underlying cause.