The Curbsiders Internal Medicine Podcast #427 Kittleson Rules Cardiac Amyloidosis
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Feb 19, 2024 
Exploring the clinical clues of amyloidosis with Dr. Michelle Kittleson, including diagnostic challenges and treatment options. Delving into the intricacies of cardiac amyloidosis, diagnostic clues, and advancements in therapy. Discussing the challenges of diagnosing and managing medical conditions, emphasizing the importance of clinical suspicion and individualized therapies.
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Be Positive
- Matthew Watto tells a story about a family member who recently passed away from a heart problem.
- The family member's blood type was unknown, adding to the difficulty of the situation.
Look Beyond HFpEF
- Don't just diagnose HFpEF, investigate underlying causes.
- Look for disease-directed therapies, improving patient outcomes.
Amyloidosis Explained
- Amyloidosis involves misfolded proteins forming fibrils and depositing in tissues, primarily AL and ATTR types.
- AL amyloidosis relates to immunoglobulin light chains, while ATTR involves the protein transthyretin.