Inhibiting DPP4 can boost GLP1 levels by preventing the rapid breakdown of GLP1 by the DPP4 enzyme. Strategies to inhibit DPP4 can have significant implications, such as enhancing the effectiveness of drugs like Ozempic. By focusing on three main approaches - increasing L cells, promoting more GLP1 production from each L cell, and inhibiting DPP4 breakdown - we can optimize GLP1 levels. One effective method is consuming more fiber to stimulate the production of short-chain fatty acids, which in turn promote the differentiation of more L cells in the gut, ultimately supporting the gut microbiome.

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