Genetic Influence on Methylation and Folic Acid

Genes play a crucial role in methylation, with common mutations like MTHFR affecting the conversion of folic acid to methylfolate. The MTHFR mutation is prevalent in 40-60% of the population, disrupting the conversion process. Folic acid is a synthetic compound added to many foods since 1993, unlike natural folate. Understanding genetic mutations like MTHFR can help in supplementing deficiencies effectively.