The Proof with Simon Hill cover image

Are lectins toxic? | Alan Flanagan, PhD & Matthew Nagra, Nd

The Proof with Simon Hill

Understanding the Limitations of Lectins and Intestinal Permeability Studies

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Certain lectins found in foods are believed to bind to toll-like receptors, triggering inflammation and potentially leading to intestinal permeability, as demonstrated in preclinical studies. However, the effects observed in these studies may not directly translate to the functioning of the human body. While markers of intestinal permeability may increase in individuals with gluten sensitivities, this does not apply to the majority of the population. It is important to note that similar effects can be caused by bacterial endotoxins in meat, raising questions about the broader context of research findings.

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