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JAMA Clinical Reviews cover image

Obesity Medications

JAMA Clinical Reviews

NOTE

Managing Semaglutide Treatment and Lifestyle Changes

The decision-making process between a patient and clinician regarding semaglutide treatment is crucial, as abruptly stopping the medication can lead to regaining lost weight. Research is exploring alternative therapies like intermittent dosing, reducing to a minimally effective dose, or switching to a more cost-effective oral medication. Emphasizing lifestyle changes such as calorie monitoring, exercise, and meal planning is essential to maintain muscle mass. Strategies like setting up environments to avoid tempting foods, monitoring diet, and long-term use considerations are key aspects to focus on.

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