JAMA Clinical Reviews

Obesity Medications

27 snips
Jul 22, 2024
Dr. Robert F. Kushner from Northwestern University discusses new weight-loss drugs for obesity management. Topics include nutrient-stimulated hormone-based meds, less common medications, comparing terzepatide to semaglutide, and future weight loss drug advancements. The focus is on improving overall health outcomes with successful interventions.
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INSIGHT

Hormone-Mimicking Obesity Drugs

  • New obesity medications mimic entero-pancreatic hormones like GLP-1 to reduce appetite and gastric emptying.
  • These drugs revolutionize obesity treatment with high effectiveness and once-weekly self-injection.
ADVICE

Managing Medication Side Effects

  • Manage gastrointestinal side effects by slow dose escalation and healthy diet counseling.
  • Plan meals with small, low-fat portions and avoid eating out immediately after injection to reduce side effects.
ADVICE

Meal Planning for Medication Tolerance

  • Plan your meal structure with three meals daily, possibly with snacks, small portions, and healthy foods.
  • Avoid dining out on injection days to maintain control over meals and reduce medication side effects.
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