Science Magazine Podcast

Science Magazine
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Oct 1, 2020 • 31min

FDA clinical trial protection failures, and an AI that can beat curling’s top players

Investigative journalist Charles Piller joins host Sarah Crespi to discuss his latest Science exclusive: a deep dive into the Food and Drug Administration’s protection of human subjects in clinical trials. Based on months of data analysis and interviews, he uncovered long-term failures in safety enforcement in clinical trials and potential problems with trial data used to make decisions about drug and device approvals. Sarah also talks with Klaus-Robert Müller, a professor of machine learning at the Technical University of Berlin, about an artificial intelligence (AI) trained in the sport of curling—often described as a cross between bowling and chess. Although AI has succeeded in chess, Go, and poker, the constantly changing environment of curling is far harder for a nonhuman mind to adapt to. But AIs were the big winners in competitions with top human players, Müller and colleagues report this week in Science Robotics. This week’s episode was produced with help from Podigy. Listen to previous podcasts. About the Science Podcast Download a transcript (PDF).    ++Meta   [Image: Cory Denton/Flickr; Music: Jeffrey Cook]   Authors: Sarah Crespi; Charles Piller   Learn more about your ad choices. Visit megaphone.fm/adchoices
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Sep 24, 2020 • 24min

How Neanderthals got human Y chromosomes, and the earliest human footprints in Arabia

Contributing Correspondent Ann Gibbons talks with host Sarah Crespi about a series of 120,000-year-old human footprints found alongside prints from animals like asses, elephants, and camels in a dried-up lake on the Arabian Peninsula. These are the earliest human footprints found so far in Arabia and may help researchers better understand the history of early hominin migrations out of Africa. Continuing on the history of humanity theme, Sarah talks with Janet Kelso of the Max Planck Institute for Evolutionary Anthropology, about her team’s efforts to fish the elusive Y chromosome out of Neanderthal and Denisovan DNA. It turns out Y chromosomes tell a different story about our past interbreeding with Neanderthals than previous tales told by the rest of the genome. Read a related Insight article. This week’s episode was produced with help from Podigy. Listen to previous podcasts. About the Science Podcast Download a transcript (PDF). [Image: Stuart Rankin/Flickr; Music: Jeffrey Cook] Authors: Sarah Crespi; Ann Gibbons Learn more about your ad choices. Visit megaphone.fm/adchoices
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Sep 17, 2020 • 26min

Performing magic for animals, and why the pandemic is pushing people out of prisons

Staff Writer Kelly Servick joins host Sarah Crespi to discuss how jail and prison populations in the United States have dropped in the face of coronavirus and what kinds of scientific questions about public health and criminal justice are arising as a result. Also this week, Elias García-Pelegrín, a Ph.D. student at the University of Cambridge, talks with Sarah about his article on watching animals watch magic tricks. Do animals fall for the same illusions we do? What does it say about the way their minds work? This week’s episode was produced with help from Podigy. Listen to previous podcasts. About the Science Podcast Download a transcript (PDF). Learn more about your ad choices. Visit megaphone.fm/adchoices
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Sep 10, 2020 • 27min

Alien hunters get a funding boost, and checking on the link between chromosome ‘caps’ and aging

First up this week, Senior Correspondent Daniel Clery talks with host Sarah Crespi about how Breakthrough Listen—a privately funded initiative that aims to spend $100 million over 10 years to find extraterrestrial intelligent life—has changed the hunt for alien intelligence-link.  And as part of a special issue on the Genotype-Tissue Expression  (GTEx) Project, Brandon Pierce, a professor in the Departments of Public Health Sciences and Human Genetics at the University of Chicago, joins Sarah to discuss his group’s work on variation in the protective caps at the end of our chromosomes. The gradual shortening of these caps, also known as telomeres, has been associated with aging.  Read more from the GTEx special issue. This week’s episode was produced with help from Podigy. Listen to previous podcasts About the Science Podcast Download a transcript (PDF) [Image: V. Altounian/Science; Music: Jeffrey Cook] Authors: Sarah Crespi; Dan Clery Learn more about your ad choices. Visit megaphone.fm/adchoices
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Sep 3, 2020 • 32min

Fighting Europe’s second wave of COVID-19, and making democracy work for poor people

First up this week, Contributing Correspondent Kai Kupferschmidt talks with host Sarah Crespi about rising numbers of coronavirus cases in Europe. Will what we’ve learned this summer about how the virus is transmitted and treated help prevent a second peak? Read all of our coronavirus news coverage.  And as part of a special issue on democracy, Rohini Pande, a professor in the department of economics at Yale University, joins Sarah to discuss her review that asks the question: Can democracy work for poor people? Read more from the special issue on democracy. This week’s episode was produced with help from Podigy. Listen to previous podcasts. About the Science Podcast Download a transcript (PDF). [Image: Mattias Berg/Flickr; Music: Jeffrey Cook] Authors: Sarah Crespi; Kai Kupferschmidt Learn more about your ad choices. Visit megaphone.fm/adchoices
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Aug 27, 2020 • 34min

Arctic sea ice under attack, and ancient records that can predict the future effects of climate change

Staff Writer Paul Voosen talks with host Sarah Crespi about how Arctic sea ice is under attack from above and below—not only from warming air, but also dangerous hot blobs of ocean water. Next, Damien Fordham, a professor and global change ecologist at the University of Adelaide, talks about how new tools for digging into the past are helping catalog what happened to biodiversity and ecosystems during different climate change scenarios in the past. These findings can help predict the fate of modern ecosystems under today’s human-induced climate change. And in our books segment, Kiki Sanford talks with author Carl Bergstrom about his new book: Calling Bullshit: The Art of Skepticism in a Data-Driven World. This week’s episode was produced with help from Podigy. Listen to previous podcasts. About the Science Podcast Download a transcript (PDF). Learn more about your ad choices. Visit megaphone.fm/adchoices
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Aug 20, 2020 • 27min

Wildlife behavior during a global lockdown, and electric mud microbes

First up this week, Staff Writer Erik Stokstad joins host Sarah Crespi to talk about how wildlife biologists are taking advantage of humanity’s sudden lull. Scientists are launching studies of everything from sea turtles on suddenly quiet beaches to noise-averse birds living near airports to see how animal behavior changes when people are a little less obtrusive. Read all of our coronavirus coverage here. Next, as part of our special issue on mud—yes, wet dirt— Senior Correspondent Elizabeth Pennisi talks about her story on electric microbes that were first found in mud and are now found pretty much everywhere. Why do bacteria need to move electrons around and what does it mean that they do it all over the planet? This week’s episode was produced with help from Podigy. Listen to previous podcasts. About the Science Podcast Download a transcript (PDF). Image: Lars Riis-Damgaard and Steffen Larsen; Music: Jeffrey Cook Authors: Sarah Crespi; Liz Pennisi; Erik Stokstad Learn more about your ad choices. Visit megaphone.fm/adchoices
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Aug 13, 2020 • 30min

A call for quick coronavirus testing, and building bonds with sports

Staff Writer Robert Service talks with host Sarah Crespi about a different approach to COVID-19 testing that might be useful in response to the high numbers of cases in the United States. To break chains of transmission and community spread, the new strategy would replace highly accurate but slow polymerase chain reaction (PCR) tests with cheaper, faster tests that are less accurate but can be administered frequently. Such tests cost between $1 and $3 compared with more than $100 for diagnostic PCR tests and give results in less than 30 minutes instead of days. Read all of our coronavirus coverage here. Also this week, Salma Mousa, a postdoctoral fellow at Stanford University, joins Sarah to talk about an experiment that added Muslim players to teams in a Christian soccer league in northern Iraq. The goal of the study was to see whether this type of social contact would change how the Christians—a threatened minority in the region—behaved toward Muslims, on and off the field. This week’s episode was produced with help from Podigy. Listen to previous podcasts. About the Science Podcast Download a transcript (PDF). [Image: Kate Brady/Flickr; Music: Jeffrey Cook] Authors: Sarah Crespi; Robert Service Learn more about your ad choices. Visit megaphone.fm/adchoices
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Aug 6, 2020 • 30min

Why COVID-19 poses a special risk during pregnancy, and how hair can split steel

Staff Writer Meredith Wadman joins host Sarah Crespi to discuss the risk of the novel coronavirus infection to pregnant women. Early data suggest expectant women are more likely to get severe forms of the infection and require hospitalization. Meredith describes how the biology of pregnancy—such as changes to the maternal immune system and added stress on the heart and lungs—might explain the harsher effects of the virus. Also this week, Sarah talks with Gianluca Roscioli about his experiments with commercial razor blades and real human hair. By using a scanning electron microscope, he was able to show how something relatively soft like hair is able to damage something 50 times harder like stainless steel. This week’s episode was produced with help from Podigy. Listen to previous podcasts. About the Science Podcast Download a transcript (PDF). [Image: G. Roscioli et al., Science 2020; Music: Jeffrey Cook] Authors: Sarah Crespi; Meredith Wadman Episode page: https://www.sciencemag.org/podcast/why-covid-19-poses-special-risk-during-pregnancy-and-how-hair-can-split-steel   Learn more about your ad choices. Visit megaphone.fm/adchoices
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Jul 30, 2020 • 38min

Fighting COVID-19 vaccine fears, tracking the pandemic’s origin, and a new technique for peering under paint

Science Editor-in-Chief Holden Thorp joins host Sarah Crespi to discuss his editorial on preventing vaccine hesitancy during the coronavirus pandemic. Even before the current crisis, fear of vaccines had become a global problem, with the World Health Organization naming it as one of the top 10 worldwide health threats in 2019. Now, it seems increasingly possible that many people will refuse to get vaccinated. What can public health officials and researchers do to get ahead of this issue? Also this week, Sarah talks with Science Senior Correspondent Jon Cohen about his story on Chinese scientist Shi Zhengli, the bat researcher at the center of the COVID-19 origins controversy—and why she thinks President Donald Trump owes her an apology. Finally, Geert Van der Snickt, a professor in the conservation-restoration department at the University of Antwerp, talks with Sarah about his Science Advances paper on a new process for peering into the past of paintings. His team used a combination of techniques to look beneath an overpainting on the Ghent Altarpiece by Hubert and Jan Van Eyck—a pivotal piece that showed the potential of oil paints and even included an early example of painting from an aerial view. This week’s episode was produced with help from Podigy. Listen to previous podcasts. About the Science Podcast Download a transcript (PDF). [Image: van der Snickt et al., Science Advances 2020; Music: Jeffrey Cook] Learn more about your ad choices. Visit megaphone.fm/adchoices

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