

Depresh Mode with John Moe
John Moe, Maximum Fun
Join host John Moe (The Hilarious World of Depression) for honest, relatable, and, yes, sometimes funny conversations about mental health. Hear from comedians, musicians, authors, actors, and other top names in entertainment and the arts about living with depression, anxiety, and many other common disorders. Find out what they’ve done to address it, what worked, and what didn’t. Depresh Mode also features useful insights on mental health issues with experts in the field. It’s honest talk from people who have been there and know their stuff. No shame, no stigma, and more laughs than you might expect.
Episodes
Mentioned books

Dec 8, 2025 • 36min
Unemployment Hurts Mental Health, Horror Movies Might Help It. Really!
Christina Caron, a New York Times mental health reporter, discusses the profound impact of long-term unemployment on mental health, including its links to depression and anxiety. She offers insights on reframing job loss and building a support network. Joining her is Terri Rivera, co-owner of the Horror Bodega, who shares how horror movies can be surprisingly therapeutic. Her creative support groups use film clips to help participants externalize feelings and normalize emotional check-ins, demonstrating a unique approach to coping with mental health challenges.

Dec 1, 2025 • 45min
Maureen Johnson Became Friends with Her Anxiety Monster
Maureen Johnson loves mysteries. Loves reading classic detective fiction and loves writing mystery stories, which young readers have been gobbling up for years. Some of Maureen’s stories feature teenage sleuth Stevie Bell, who, besides having a knack for solving cold cases, deals with an anxiety disorder. It’s not all there is to Stevie, of course, but it’s definitely there and she has to manage it on an ongoing basis. Maureen tells us about Stevie and about her own recent anxiety mystery when she was suddenly whomped by a massive wave of anxiety that would not go away and severely affected her life for quite a while. Faced with that mystery, Maureen got to work gathering clues to figure it out, ultimately finding many effective techniques, including to fighting the anxiety monster (which she visualizes as Gossamer, the big red furry monster from Bugs Bunny cartoons) but welcoming it, getting to know it, and finding out what made it tick. She also got some lab work done, which pointed to a pronounced iron problem that was fixable.Thank you to all our listeners who support the show as monthly members of Maximum Fun.Check out our I’m Glad You’re Here and Depresh Mode merchandise at the brand new merch website MaxFunStore.com!Hey, remember, you’re part of Depresh Mode and we want to hear what you want to hear about. What guests and issues would you like to have covered in a future episode? Write us at depreshmode@maximumfun.org.Depresh Mode is on BlueSky, Instagram, Substack, and you can join our Preshies Facebook group. Help is available right away.The National Suicide Prevention Lifeline: 988 or 1-800-273-8255, 1-800-273-TALKCrisis Text Line: Text HOME to 741741.International suicide hotline numbers available here: https://www.opencounseling.com/suicide-hotlines

Nov 26, 2025 • 18min
A Holiday Family Survival Mini-sode
Yes, the holidays are upon us. Getting together with family can be a wonderful, loving experience. It can also be a lot. There can be old grudges, chafing at family roles, the specter of politics might play in. We’re here to help. In This Family is a podcast produced by our host, John Moe, for Nexus Family Healing, a mental health nonprofit based in the Twin Cities. It’s all about the connections between family and mental health.In this miniature episode, that show’s host, Dr. Michelle K. Murray goes over some good ways to manage your boundaries, take care of yourself, and have a good time. Dr. Murray is a licensed family and marriage therapist and CEO of Nexus Family Healing. Give this short episode a quick listen in the car on the way to see family and give In This Family a listen. You’ll find episodes with some Depresh Mode favorite guests like Maria Bamford and Gary Gulman and some new voices you’ll enjoy.Thank you to all our listeners who support the show as monthly members of Maximum Fun.Check out our I’m Glad You’re Here and Depresh Mode merchandise at the brand new merch website MaxFunStore.com!Hey, remember, you’re part of Depresh Mode and we want to hear what you want to hear about. What guests and issues would you like to have covered in a future episode? Write us at depreshmode@maximumfun.org.Depresh Mode is on BlueSky, Instagram, Substack, and you can join our Preshies Facebook group. Help is available right away.The National Suicide Prevention Lifeline: 988 or 1-800-273-8255, 1-800-273-TALKCrisis Text Line: Text HOME to 741741.International suicide hotline numbers available here: https://www.opencounseling.com/suicide-hotlines

Nov 24, 2025 • 1h 2min
Esmé Weijun Wang’s Mind Convinced Her She Was Dead and In the Afterlife
Cotard’s delusion, also known as Cotard’s syndrome, is an extremely rare condition where the patient believes that they are actually dead. For the bestselling author Esmé Weijun Wang, Cotard’s came along after she had already been traveling a difficult road that involved schizoaffective disorder along with a host of other mental health issues. While experiencing Cotard’s, Esmé urgently told her husband that he was dead too and so was their dog. She believed, was certain, that the life she was experiencing was kind of a simulation where she had to prove herself worthy of a second chance and not an eternity in Hell. We also hear about the shocking way Yale handled Esmé’s mental health and about the trauma very early in childhood that she thinks led to the complex PTSD that fueled a lot of her mental health challenges.Thank you to all our listeners who support the show as monthly members of Maximum Fun.Check out our I’m Glad You’re Here and Depresh Mode merchandise at the brand new merch website MaxFunStore.com!Hey, remember, you’re part of Depresh Mode and we want to hear what you want to hear about. What guests and issues would you like to have covered in a future episode? Write us at depreshmode@maximumfun.org.Depresh Mode is on BlueSky, Instagram, Substack, and you can join our Preshies Facebook group. Help is available right away.The National Suicide Prevention Lifeline: 988 or 1-800-273-8255, 1-800-273-TALKCrisis Text Line: Text HOME to 741741.International suicide hotline numbers available here: https://www.opencounseling.com/suicide-hotlines

Nov 17, 2025 • 60min
Is Your Mental Health Diagnosis an Identity or Something More Meaningless?
Join Sarah Fay, an author and mental health advocate, as she challenges the validity of mental health diagnoses and their impact on personal identity. Sarah shares her journey of being labeled with various disorders, revealing how these identities shaped her behavior and recovery path. She argues against the chemical imbalance theory and criticizes the DSM's labels, advocating for a focus on recovery rather than diagnosis. Through her experiences, she highlights the need for systemic change in mental health treatment and the importance of questioning labels.

Nov 10, 2025 • 38min
The Personal Side of Huge Cuts to Addiction, Suicide Prevention, and Mental Health Programs
Over half the employees at the Substance Abuse and Mental Health Services Administration (SAMHSA) who were there in January are now gone, include 12 of the 17 senior leaders. SAMHSA is in charge of distributing and administering mental health programs around the country and the cuts to both staffing and to the programs the agency serves have meant many programs addressing addiction and suicide prevention being severely hobbled or shutting down altogether. In turn, that means fewer people getting help and more people suffering. O. Rose Broderick, Disability and Healthcare Reporting Fellow at Stat, joins us to explain the cuts, why they may be happening, and the extremely fragile state of these programs in America today. Rose also share her own connection to mental health, the struggles her own family has endured, and why all mental health stories are, at their heart, personal matters.Thank you to all our listeners who support the show as monthly members of Maximum Fun.Check out our I’m Glad You’re Here and Depresh Mode merchandise at the brand new merch website MaxFunStore.com!Hey, remember, you’re part of Depresh Mode and we want to hear what you want to hear about. What guests and issues would you like to have covered in a future episode? Write us at depreshmode@maximumfun.org.Depresh Mode is on BlueSky, Instagram, Substack, and you can join our Preshies Facebook group. Help is available right away.The National Suicide Prevention Lifeline: 988 or 1-800-273-8255, 1-800-273-TALKCrisis Text Line: Text HOME to 741741.International suicide hotline numbers available here: https://www.opencounseling.com/suicide-hotlines

Nov 3, 2025 • 41min
Seasonal Affective Disorder and Why It Sucks So Bad
When we went looking for information on the condition known as seasonal affective disorder, or SAD, one of the first things we noticed was that some people aren’t even calling it that anymore. The website for the National Alliance on Mental Illness (NAMI), for instance, uses the term “major depressive disorder with a seasonal pattern”, which means an acronym of MDDWASP. Here at Depresh Mode, we’re perfectly fine referring to it as “mud wasp”. On this episode of the show, we talk with NAMI’s chief medical officer, Dr. Ken Duckworth, about how it’s similar to and different from traditional depression and what one could do to deal with it. With Ken, we discuss the less common and less understood spring and summer variety of MDDWASP. We also hear from Joy and Christina from our Preshies group on Facebook about their experiences.Thank you to all our listeners who support the show as monthly members of Maximum Fun.Check out our I’m Glad You’re Here and Depresh Mode merchandise at the brand new merch website MaxFunStore.com!Hey, remember, you’re part of Depresh Mode and we want to hear what you want to hear about. What guests and issues would you like to have covered in a future episode? Write us at depreshmode@maximumfun.org.Help is available right away.The National Suicide Prevention Lifeline: 988 or 1-800-273-8255, 1-800-273-TALKCrisis Text Line: Text HOME to 741741.International suicide hotline numbers available here: https://www.opencounseling.com/suicide-hotlinesThe Depresh Mode newsletter is available twice a week. Subscribe for free and stay up to date on the show and mental health issues. https://johnmoe.substack.com/John’s acclaimed memoir, The Hilarious World of Depression, is now available in paperback. https://us.macmillan.com/books/9781250209566/thehilariousworldofdepressionFind the show on X @depreshpod and Instagram @depreshpod.John is on X @johnmoe.

Oct 27, 2025 • 48min
Is Whiteness a Mental Health Problem? Dr. Jonathan Mathias Lassiter Thinks So.
It’s a question we ask a lot on this show: do you have a mental health problem or is the problem actually rooted in the world you live in? Psychologist Dr. Jonathan Mathias Lassiter says contemporary society lives under three different assumptions: there’s not enough to go around, kill or be killed, and us versus them or divide and conquer and this results in people valuing individualism, competition, and materialism. This way of living, he says, is a result of white dominance or whiteness and it is a distortion of the way humans are meant to live and therefore leads to things like racism, sexism, homophobia, and the brutality of human beings to one another. Dr. Lassiter, author of How I Know White People Are Crazy and Other Stories says whiteness is not a mental health disorder but it is a mental health problem that we all need to face. Dr. Lassiter tells his own story, growing up with a chronic illness, gay, and Black in the South and eventually earning his PhD. in psychology. As he came to understand psychology and the way the world works, he noticed the impact of society’s built-in obstacles on his own mental health journey and among the students and clients he has helped.Thank you to all our listeners who support the show as monthly members of Maximum Fun.Check out our I’m Glad You’re Here and Depresh Mode merchandise at the brand new merch website MaxFunStore.com!Hey, remember, you’re part of Depresh Mode and we want to hear what you want to hear about. What guests and issues would you like to have covered in a future episode? Write us at depreshmode@maximumfun.org.Depresh Mode is on BlueSky, Instagram, Substack, and you can join our Preshies Facebook group. Help is available right away.The National Suicide Prevention Lifeline: 988 or 1-800-273-8255, 1-800-273-TALKCrisis Text Line: Text HOME to 741741.International suicide hotline numbers available here: https://www.opencounseling.com/suicide-hotlines

Oct 20, 2025 • 42min
Is the U.S. Government Going To Take Away Your Antidepressants?
Robert F. Kennedy, Jr., the Secretary of Health and Human Services, clearly does not like SSRIs (selective serotonin reuptake inhibitors), the most popular form of antidepressant on the market. They’re used by millions of Americans on a daily basis. He has tried to tie SSRIs to school shooters despite a lack of evidence to that effect. He has suggested that it’s harder to go off SSRIs than it is to quit heroin. It’s not. Molly Olmstead, a reporter for Slate who has been covering this story closely, says that this does not mean that the government is about to try to ban SSRIs and leave patients without the medicines that may be keeping them alive. But she explains that yes, we are in the midst of a very active anti-SSRI PR campaign by Kennedy and his supporters in the so-called Make America Healthy Again movement and that campaign could presage a much more aggressive set of actions.Thank you to all our listeners who support the show as monthly members of Maximum Fun.Check out our I’m Glad You’re Here and Depresh Mode merchandise at the brand new merch website MaxFunStore.com!Hey, remember, you’re part of Depresh Mode and we want to hear what you want to hear about. What guests and issues would you like to have covered in a future episode? Write us at depreshmode@maximumfun.org.Depresh Mode is on BlueSky, Instagram, Substack, and you can join our Preshies Facebook group. Help is available right away.The National Suicide Prevention Lifeline: 988 or 1-800-273-8255, 1-800-273-TALKCrisis Text Line: Text HOME to 741741.International suicide hotline numbers available here: https://www.opencounseling.com/suicide-hotlines

Oct 13, 2025 • 56min
P.E. Moskowitz on Whether Your Mind is Broken or the World Is
P.E. Moskowitz, an insightful author and journalist known for tackling mental health and urban issues, delves into the complexities of trauma in this thought-provoking conversation. They share personal experiences from witnessing violence during the Charlottesville protests and the 9/11 attacks, linking these events to their struggles with mental health. Moskowitz challenges conventional views on treatment, emphasizing the need for better coping mechanisms and access to diverse therapeutic options, while also exploring the societal meanings behind drug use.


