
Depresh Mode with John Moe
Join host John Moe (The Hilarious World of Depression) for honest, relatable, and, yes, sometimes funny conversations about mental health. Hear from comedians, musicians, authors, actors, and other top names in entertainment and the arts about living with depression, anxiety, and many other common disorders. Find out what they’ve done to address it, what worked, and what didn’t. Depresh Mode also features useful insights on mental health issues with experts in the field. It’s honest talk from people who have been there and know their stuff. No shame, no stigma, and more laughs than you might expect.
Latest episodes

May 12, 2025 • 41min
The Head And The Heart’s Kenny Hensley Injured Both Shoulders and That’s Where the Trouble Started
Aperture is the sixth studio album by the indie-folk band The Head And The Heart and it’s kind of a return to the more grounded, collaborative sound of their earliest work. It’s less polished, less highly produced, not as poppy. That’s not an accident. The band has been putting in the work to be more of a cohesive unit by sharing songwriting and singing duties, going to therapy together, and trying to closely protect the health of both the individual members and the group itself. Kenny Hensley joins us to talk about the shoulder injuries he incurred, a dangerous xanax habit that followed, some unpleasant incidents that resulted from that, his suspension from The Head And The Heart, and his return to good health and a productive role.Thank you to all our listeners who support the show as monthly members of Maximum Fun.Check out our I’m Glad You’re Here and Depresh Mode merchandise at the brand new merch website MaxFunStore.com!Hey, remember, you’re part of Depresh Mode and we want to hear what you want to hear about. What guests and issues would you like to have covered in a future episode? Write us at depreshmode@maximumfun.org.Depresh Mode is on BlueSky, Instagram, Substack, and you can join our Preshies Facebook group. Help is available right away.The National Suicide Prevention Lifeline: 988 or 1-800-273-8255, 1-800-273-TALKCrisis Text Line: Text HOME to 741741.International suicide hotline numbers available here: https://www.opencounseling.com/suicide-hotlines

May 5, 2025 • 39min
988’s Future, Funding, and Online Fables
There have been ten million contacts, via phone calls, texts, and chats, with the 988 Suicide & Crisis Lifeline since it first launched in July of 2022. As its third anniversary approaches, we check in to see how the system is holding up, what the funding and capacity issues are, and what the future might look like with our guest, Hannah Wesolowski, Chief Advocacy Officer for the National Alliance on Mental Illness (NAMI). We also examine the potential threat to the LGBTQ specialized services line after a leaked document from the Trump administration proposed cutting funding for it. And we debunk an internet meme involving cutting all 988 funding and Canada stepping in to pick up America’s slack.Thank you to all our listeners who support the show as monthly members of Maximum Fun.Check out our I’m Glad You’re Here and Depresh Mode merchandise at the brand new merch website MaxFunStore.com!Hey, remember, you’re part of Depresh Mode and we want to hear what you want to hear about. What guests and issues would you like to have covered in a future episode? Write us at depreshmode@maximumfun.org.Depresh Mode is on BlueSky, Instagram, Substack, and you can join our Preshies Facebook group. Help is available right away.The National Suicide Prevention Lifeline: 988 or 1-800-273-8255, 1-800-273-TALKCrisis Text Line: Text HOME to 741741.International suicide hotline numbers available here: https://www.opencounseling.com/suicide-hotlines

Apr 28, 2025 • 48min
Generative AI Chatbot Delivers Great Results for Mental Health. Is “Therabot” the Future?
Would you open your heart to a bot? Tell it all your problems? Look to a piece of code, a computer program, for high-quality mental healthcare? Some people have said yes and the results are hard to ignore. Dartmouth University test subjects who sought help from Therabot, a generative AI chatbot, showed a 51% reduction in depression symptoms, 31% for anxiety, 19% for eating disorders. Dr. Nicholas Jacobson, who led the study, says people really bonded with Therabot, called it Thera for short, and would check in with it frequently. But can a bot really provide meaningful advice and therapy if it’s not a human being? Are you now interested in Therabot or more likely than ever to stay far away?This episode mentions ELIZA, an early ancestor of Therabot from 1966. You can take Eliza for a spin here.Thank you to all our listeners who support the show as monthly members of Maximum Fun.Check out our I’m Glad You’re Here and Depresh Mode merchandise at the brand new merch website MaxFunStore.com!Hey, remember, you’re part of Depresh Mode and we want to hear what you want to hear about. What guests and issues would you like to have covered in a future episode? Write us at depreshmode@maximumfun.org.Depresh Mode is on BlueSky, Instagram, Substack, and you can join our Preshies Facebook group. Help is available right away.The National Suicide Prevention Lifeline: 988 or 1-800-273-8255, 1-800-273-TALKCrisis Text Line: Text HOME to 741741.International suicide hotline numbers available here: https://www.opencounseling.com/suicide-hotlines

Apr 21, 2025 • 48min
Perfectly Hidden Depression: Do You Have It? With Dr. Margaret Rutherford
If you were brought up in a family or a culture that never recognized, discussed, or processed things like depression and trauma, you may have learned to simply hide those difficult feelings away and simply act as if everything’s great. You can be a high achiever, striving perfection, all to keep away demons that you’ve never really faced. Your act can be so good that it even fools you. For a while, anyway. Until it doesn’t. And then things can get very ugly. Psychologist Dr. Margaret Rutherford coined the term Perfectly Hidden Depression several years ago in a blog post that instantly went viral, filling her inbox with people shocked to recognize their own lives in what she described. She joins us to talk about PHD, how to recognize it in yourself, and what to do about it.Thank you to all our listeners who support the show as monthly members of Maximum Fun.Check out our I’m Glad You’re Here and Depresh Mode merchandise at the brand new merch website MaxFunStore.com!Hey, remember, you’re part of Depresh Mode and we want to hear what you want to hear about. What guests and issues would you like to have covered in a future episode? Write us at depreshmode@maximumfun.org.Depresh Mode is on BlueSky, Instagram, Substack, and you can join our Preshies Facebook group. Help is available right away.The National Suicide Prevention Lifeline: 988 or 1-800-273-8255, 1-800-273-TALKCrisis Text Line: Text HOME to 741741.International suicide hotline numbers available here: https://www.opencounseling.com/suicide-hotlines

Apr 14, 2025 • 44min
Cameron Esposito on Comedy, Rehab, and Bipolar Disorder
Cameron Esposito, a stand-up comedian, actor, writer, and podcast host, shares her journey after a recent bipolar disorder diagnosis. She discusses the transformative effects of medication on her social life and creative expression. The conversation dives into her rehab experience, highlighting the balance between recovery and career pressures. Cameron’s new special, 'Four Pills', reflects on using humor to navigate mental health challenges, showcasing how personal experiences heavily influence her comedic style. It’s an enlightening and humorous exploration of life with bipolar disorder.

Apr 7, 2025 • 38min
The Thorny Issue of Airline Pilots and Mental Illness
Dr. Helen Ouyang, a physician and associate professor at Columbia University, dives into the heavy topic of mental health in the aviation industry. She highlights the stigma airline pilots face when dealing with mental illness and the fear of job loss if they seek help. Ouyang shares compelling stories of pilots who've navigated these challenges and discusses the urgent need for reform in mental health support within aviation. The conversation shifts to self-care and wellness, offering listeners practical tips and a fun look at resources like the Finch app.

Mar 31, 2025 • 49min
Hanif Abdurraqib on Cultivating a Support System, Depression, Anxiety, and Basketball
Hanif Abdurraqib, a MacArthur Fellow and acclaimed poet, opens up about his journey with depression and anxiety. He emphasizes the vital role of community and support networks in mental health care. Hanif shares personal anecdotes about how basketball has shaped his identity and offers strategies for managing anxiety, including the importance of routines and physical activity. He encourages listeners to find joy in small moments and highlights the significance of recognizing and nurturing supportive relationships.

Mar 26, 2025 • 20min
Checking in With Friends: Open Mike Eagle
Open Mike Eagle, a talented rapper, comedian, and podcast host, dives into the current turmoil affecting society. He discusses how chaos in the news influences creativity and mental health while highlighting the struggles within the entertainment industry. Open Mike also emphasizes the significance of community and intentional self-reflection in navigating emotional well-being during tough times. The conversation culminates in a call for connection and support, showcasing the power of reaching out to friends and sharing experiences.

Mar 25, 2025 • 6min
Welcome, New Listeners
New listeners are warmly welcomed as the discussion dives into universal mental health challenges. The hosts emphasize the importance of open dialogue and personal stories, making everyone feel included. They aim to create a supportive community that blends humor with heartfelt conversations. Listeners are encouraged to share their thoughts on future topics while participating in a fundraising drive to enhance the show's reach and impact. It's about connection, openness, and embracing the journey together.

Mar 24, 2025 • 1h 3min
Jim James of My Morning Jacket on Depression, EMDR, Gratitude, and Taking Care of Jim
Jim James, the lead singer of My Morning Jacket, shares his candid journey through depression and alcoholism, emphasizing the importance of self-compassion. He reflects on seeking validation and how intense therapy, including EMDR, has reshaped his outlook. James discusses the therapeutic power of music, mindfulness on tour, and the struggles of finding the right therapist. With a focus on gratitude and support, he encourages listeners to embrace their journeys to mental wellness.