Everyday Wellness: Midlife Hormones, Health, and Science for Women 35+

Today I am honored to connect with my good friend and multiple-time past guest, Ben Azadi! Ben was most recently with me on Podcasts #149 and #101. He is a prolific social media star and a fasting and ketogenic dieting expert. He is known as “The Health Detective” because he investigates dysfunction and educates, not medicates, to return the body to normal function. Ben is the founder of Keto Kamp and the popular Keto Kamp podcast.Today, Ben and I use an Ask Me Anything format and dive into listener questions. We talk about the nuances of macronutrients, fasting, and supplements. We discuss gut health and how changing your diet and intermittent fasting can help the body realign and be better balanced. We get into troubleshooting with fasting, including insomnia-related issues, and we also discuss the DUTCH test and how it can be beneficial in conjunction with other lab tests.I love doing AMAs, and I hope you will enjoy listening to my conversation with Ben Azadi.IN THIS EPISODE YOU WILL LEARN: Serita asks how to keep her energy up while on a keto diet and fasting. Mary Julie wants to know what is happening inside her body when her ketones are 1.8, but her glucose is 115, 19 hours into a fast. How does losing sex hormones when approaching perimenopause and menopause make women less metabolically flexible? Why is it essential to stay hydrated and get enough good quality sleep every night? How circadian rhythm impacts our metabolic flexibility. How breathing exercises can help us get into the parasympathetic state. Janie would like to know how much protein her body can absorb at once and how much protein she should consume over a 24-hour period. Suzanne lives a clean lifestyle and wants to know if there is a way to shift the metabolism of estrogen away from the 4OH pathway. (She is referring to the DUTCH test. A listener asks how to use fasting to help with candida. Michaela was recently diagnosed with gallstones and has one blocked duct. She read that saturated fat is not good for her condition, so she wants to know what she can eat to stay on keto. Lena has been doing strict keto with OMAD for three months, but her GGT is very high. She asks if that could be due to fasting. Why we tend to experience insomnia while doing a ketogenic diet, and how to address chronic insomnia patterns. Mary Jo wants to know when to take my creatine supplement powder. Ben and I discuss the supplements we use. Connect with Cynthia ThurlowFollow on Twitter, Instagram & LinkedInCheck out Cynthia’s websiteConnect with Ben AzadiOn his websiteOn Instagram, Facebook, LinkedIn, YouTube, TikTokThe Keto Kamp PodcastBen Azadi Speaker ReelEpisode 149 – Keto Flex, Feasting and Fasting: Bringing the Body Back to Normal Episode 101 Keto and Fasting the RIGHT Way with Ben AzadiBooks mentioned:The Circadian Diabetes Code by Dr. Satchin PandaWheat Belly by William DavisSuper Gut by William DavisBreath by James Nestor

I am honored to reconnect with Dr. Tracy Gapin today. He is a board-certified urologist and men’s health expert. The current state of metabolic health in the United States and most westernized countries has sparked a great interest in a GLP1 agonist, AKA Semaglutide Ozempic. So I wanted to talk to a clinician actively utilizing this medication.Dr. Gapin and I discuss what this drug class represents. (These are synthetic peptides.) We speak about Semaglutide, Ozempic, Wegovy, and oral Rybelsus. We get into current research, side effects, who should not take these medications, and the mechanisms of action specific to the pancreas and beta cells, reductions, gastric emptying, and the upregulation of satiety. We discuss changes in the brain regarding leptin and how these drugs work. We also talk about weight loss resistance, and I answer questions from listeners. From my perspective, it all comes back to basics. I believe that if we are to prescribe these medications, we must help our patients understand how lifestyle impacts weight-loss resistance and metabolic health. I loved that Dr. Tracy spent some time talking about the specific ways he works with his patients, even before prescribing medications. He also explains how important he has felt this drug has been for his patients.I approached today’s conversation with an open mind, and I hope you will do the same.IN THIS EPISODE YOU WILL LEARN: How the GLP1 agonists help Dr. Tracy motivate his patients to lose weight. What are GLP1 agonists, and how do they work? The physical benefits of GLP1 agonists. Who is Semaglutide not appropriate for? Some of the common side-effects of GLP1 agonists. How those who fail to implement lifestyle changes when they stop using Semaglutide may regain all the weight they lost. Why it is essential to stay hydrated when using Semaglutide. Why you need to eat enough food- protein in particular when taking Semaglutide. How to follow the metrics that matter. Some factors that could hinder successful weight loss. What Dr. Tracy does to ensure his patients do not regain the weight they lost after they stop using Semaglutide. Listener questions: Why is a diabetic drug being used for non-diabetics? Does this drug target muscle versus fat in terms of weight loss? For how long do most patients take it? Are there unique characteristics in perimenopausal and menopausal women that must be accounted for differently? Bio:Dr. Tracy Gapin is a board-certified urologist, a world-renowned men’s health & performance expert, and the founder of the Gapin Institute, the global leader in High-Performance Health. He has over 20 years of experience focused on men’s health optimization, human performance, and longevity, providing executives & entrepreneurs a personalized path to fulfill their highest potential. He’s been featured in Entrepreneur, Dave Asprey’s Biohacking Conference, and as a TEDx speaker.Connect with Cynthia ThurlowFollow on Twitter, Instagram & LinkedInCheck out Cynthia’s websiteConnect with Tracy GapinOn his websiteGapin InstituteText “Health” to 26786 to receive 10 Secrets to High-Performance Health and a free copy of Dr. Gapin’s book.

I have the honor of reconnecting with Scott Emmens today! Scott is the COO of MD Logic and a fellow health entrepreneur. Scott and I dive into Myo-inositol, one of my latest and favorite supplements! We explain what it is, its mechanism of action, and how it impacts the blood-brain barrier. We discuss its clinical considerations, relevant research regarding metabolic health, sleep, sleep architecture, and how we supplement ourselves. We also get into how we create Myo-inositol in our bodies, factors that could deplete endogenous Myo-inositol, and why supplementation can be beneficial.IN THIS EPISODE YOU WILL LEARN: What Myo-inositol is and what it does.  Why I decided to make Myo-inositol my next supplement. How does a supplement containing sugar alcohol support metabolic health? How Myo-inositol benefits metabolic health. Will it break your fast if you use Myo-inositol in a fasted state? What is the mechanism of action of Myo-inositol in the cells? How Myo-inositol impacts the blood-brain barrier and neurotransmitter pathways. How Myo-inositol may reduce inflammation and impact thought-processing. Why is it critically important to maintain metabolic health throughout our lifetime? Some natural sources of Myo-inositol. How our modern lifestyles can impact our ability to create endogenous Myo-inositol and make it harder to keep the levels optimized in the body. How Myo-inositol improves the entire sleep structure. What distinguishes MD Logic from other similar companies? Bio:Scott Emmens is the Co-Founder and Chief Operating Officer of MD Logic Health. His interest in BIOHACKING and nutrition began in college as an amateur natural bodybuilder and Biology major. While in college he sought to teach others how to stay strong, lean, and fit via recovery. It was in college he created his first fitness system and a 30-page booklet called “The Natural Body Building System” He continues to be on the cutting edge of bio-optimization and utilizes ice baths “cold immersion” photobiomodulation commonly referred to as redlight and infrared therapies among many nutrition and fasting techniques. Scott utilized his knowledge and love of biology and fitness to help drive his career in Biotech where he held a variety of roles as a Sales Leader, Disease Education Awareness Director, Director of Operations, and executive. In 2018 Scott was the lead founder of Olaregen therapeutics (Pronounced Ola-Region therapeutics.) Specializing in wound and skin care using nutrients, peptides, and collagen for a variety of skin conditions.  During his 20 years as Biotech founder and executive, Scott focused on a blend of integrative and allopathic medicine. Working within many complex therapeutic areas, including neurology, rare disease, asthma, and diabetes. Scott has held various strategic and operational roles preparing him to be both a health advocate and entrepreneur. His personal mission is to help people become their own health advocates while providing them with the knowledge and resources to be physically spiritually and emotionally fit. Ultimately leading Scott to create MD Logic Health.Connect with Cynthia ThurlowFollow on Twitter, Instagram & LinkedInCheck out Cynthia’s websiteConnect with Scott EmmensMD Logic HealthOn Instagram (@longevityprotocol)On TikTok (@collagenguru)Go to www.cynthiathurlow.com/inositol to get 25% off Myo-inositol between the 11th and the 19th of March and 15% off between the 20th and the 31st of March.Episode 244 - The Metabolic Effects of Creatine Monohydrate: Its Evidence of Efficacy for Muscle & Brain Health with Scott Emmens and Kara Lazauskas

I am happy to connect with Dr. William Li today! He is a world-renowned physician, scientist, speaker, and author. He is known for leading the Angiogenesis Foundation, and his groundbreaking work has impacted more than 70 diseases. He is also a Ted-X speaker and the author of Eat to Beat Your Diet, one of my favorite books thus far this year. Dr. Li’s latest book is about what happens in the body, how it should operate, and the steps we can take to restore the body to its hard-wired level. We dive into how body fat impacts our health, the role of metabolism throughout our lifetime, the differences between the three fat-impacting hormones, including leptin, adiponectin, and resistin, and gender differences. We speak about new drugs like Ozempic and Semaglutide, the role of brown fat, the impact of the microbiome and specific bacteria, and we also discuss nutrition and lifestyle.IN THIS EPISODE YOU WILL LEARN: Why Dr. Li chose this time to write his latest book.  Why Dr. Li believes 60 is the new 20. The four stages of metabolism all humans have been hard-wired to go through throughout their lifespan. How does excess body fat derail the metabolism, and how can we unleash our inner metabolism? Why is it better to eat slowly? Why should we learn to respect and tame our fat instead of hating or fearing it? Dr. Li shares his views on new prescription drugs like Ozempic and Semaglutide. Dr. Li shares some interesting facts about body fat. Changes that occur in our body fat distribution as we get older. How can we help our bodies fight excess body fat, let our inner metabolism come to the surface, and lower inflammation by being aware and mindful? How modern-day lifestyle choices contribute to metabolic disease. Dr. Li gets into the interplay between the gut microbiome and our metabolism and the role of Akkermansia.  Some everyday foods contain natural chemicals that can activate our body’s health defenses, tame the metabolism and fight body fat. BIOWilliam W. Li, MD, is an internationally renowned physician, scientist, and New York Times bestselling author of the forthcoming book “Eat to Beat Your Diet: Burn Fat, Heal Your Metabolism, Live Longer”. His groundbreaking work has led to the development of more than 30 new medical treatments and impacts care for more than 70 diseases, including cancer, diabetes, blindness, heart disease, and obesity. His TED Talk, “Can We Eat to Starve Cancer?” has garnered more than 11 million views. Dr. Li has appeared on Good Morning America, CNN, CNBC, LIVE with Kelly and Ryan, and the Rachael Ray Show, and he has been featured in USA Today, Time Magazine, The Atlantic, and O Magazine. He is the president and medical director of the Angiogenesis Foundation.Connect with Cynthia ThurlowFollow on Twitter, Instagram & LinkedInCheck out Cynthia’s websiteConnect with Dr. William LiOn his websiteOn social media: @DrWilliamLiDr. William Li’s latest book, Eat to Beat Your Diet: Burn Fat, Heal Your Metabolism, and Live Longer is available from most bookstores.

Today I am honored to connect with a friend and fellow nurse practitioner, Marcelle Pick! Marcelle is passionate about transforming how women experience healthcare through an integrative approach. She has successfully treated thousands of women through her unique approach to wellness.Marcelle is currently a faculty member of The Institute of Functional Medicine and has served as a Medical Advisor to Healthy Living Magazine. She has written countless articles and multiple books, including Is It Me or My Hormones?I always think of Marcelle as a pioneer in the women’s health/nurse practitioner space. In this episode, we dive into her background and the impact of the Women’s Health Initiative. We discuss the limitations of the traditional allopathic model regarding hormones, common misconceptions about adrenal health, perimenopause, and menopause, adverse childhood events and adrenal health, how lifestyle affects our sex hormones, fibroids, endometriosis, PMS, PMDD, and contraception for perimenopause. We speak about endocrine disruptors, mold, and micro toxins. We also get into ways to think about hormone replacement therapy and ways to address intimacy and low libido.I love connecting with other nurses and nurse practitioners! I hope you will love today’s conversation with Marcelle as much as I did!IN THIS EPISODE YOU WILL LEARN: Marcelle was part of the first all-women practice in the country. How the Women’s Health Initiative has impacted health care for women. The limitations of the traditional allopathic model, particularly in terms of perimenopause, menopause, and hormones. The less common labs that Marcelle likes to look at for her patients. Marcelle shares her approach to unraveling the symptoms of perimenopause. Some unique ways in which Marcelle deals with problems like fibroids and endometriosis. How childhood trauma could lead to adrenal and autoimmune issues, weight-loss resistance, and various other health problems. Many of the things Marcelle recommended for treating PMS and PMDD back in the day (1985) have now become the standard of care. Contraceptive options for women in perimenopause. The impact of stress on adrenal function during perimenopause and menopause. Marcelle dives into liver health and detoxification, chemicals and other factors that could impact our health, and changes we can make to avoid problems and feel better. What Marcelle does to help women with low libido. Connect with Cynthia ThurlowFollow on Twitter, Instagram & LinkedInCheck out Cynthia’s websiteConnect with Marcelle PickOn her website   On Facebook and InstagramAll of Marcelle’s books are available on Amazon

I am honored to reconnect with Dave Asprey today! He is the renowned father of biohacking and a New York Times bestselling author. Dave would like a world where we all have enough free time and peace to be at full power! In this episode, he and I have a no-nonsense conversation about his newest book, Smarter Not Harder, which is my favorite of all his books! We dive into the impact of the pandemic, the art and science of environment, the laziness principle, homeostasis, and the concept behind “slope with the curve” thinking. We discuss anti-nutrients, the biohacking pathway, REHIIT training, and various other cellular hacks, including hypoxification and specialized breathing, and how trauma pertains to becoming a more efficient human. I also ask Dave about his favorite supplements.I hope you enjoy listening to today’s conversation with Dave Asprey as much as I did recording it!   IN THIS EPISODE YOU WILL LEARN: Why Dave chose to write his latest book now. How Dave’s book can help you achieve homeostasis. The 5 goals in Dave’s book that he recommends for people focus on, one at a time. A fundamental mistake that people in the world of health and fitness often make.  How the “slope with the curve” biology works. How you can save energy with biohacking. The benefits of REHIT (Reduced Energy High-Intensity Interval Training). Some foods that can negatively impact our health. Dave shares his thoughts on dairy. Using hypoxification as a cellular biohack. Dave sheds some light on his favorite supplements. The role of trauma resolution. Connect with Cynthia ThurlowFollow on Twitter, Instagram & LinkedInCheck out Cynthia’s websiteConnect with Dave AspreyOn his website Danger Coffee   To open an Upgrade Labs, go to www.ownanupgradelabs.comBooks mentionedMen Are from Mars Women Are from Venus by John GrayDave’s new book, Smarter Not Harder is available from most bookstores.

I am happy to connect with Kristin Rowell today! Kristin is an attorney, Functional Nutritional Therapy Practitioner, and the CEO and Founder of Energetically Efficient. After spending 16 years building a successful business trial practice, she left to create Energetically Efficient so that she could speak to and coach other high-performers on navigating food, exercise, and other lifestyle practices efficiently.Kristin fell and broke her leg in ten places in 2013. She started meditating and received several nudges from the universe that prompted her to leave her job to pivot and transition into nutritional therapy and coaching.In this episode, she shares her pain-to-purpose story, and we dive into the role of the ego in soul work, common limiting beliefs, energy work, and why weight gain is not a normal function of aging. We also discuss how chronic stress impacts our hormones, lifestyle choices, nutritional detoxification, why muscle is the organ of longevity, and Kristin’s favorite foods to take with her when she travels.IN THIS EPISODE YOU WILL LEARN: The story behind Kristin’s career transition. Kristin discusses her process of letting go of the ego. What is energy work? Some common limiting beliefs that may prevent people from reaching their full potential. How Kristin helps people recalibrate themselves. Does gaining weight have to go along with aging? Some of the common errors Kristen sees women making.  How Kristin helps her clients detoxify naturally. How often should women do strength training? How to support yourself after a strength training workout. The foods Kristin loves to take along when she travels. Bio:Kristin Rowell is a lawyer, Functional Nutritional Therapy Practitioner, and CEO/Founder of Energetically Efficient. After spending 16 years building a successful business trial practice, she left to create Energetically Efficient so that she could speak to and coach other high-performers on how to efficiently navigate food, exercise, and other lifestyle practices to maximize their energy and become their best self each day. The foundation of Kristin's coaching centers on energy and consciousness, which makes her unique. Kristin also provides 1:1 coaching to professionals seeking to make a career transition, given that she successfully navigated that transition herself. Kristin is releasing her first cookbook this year, called Eating Efficiently. Kristin lives in Minneapolis with her two gorgeous Golden Retrievers, Catch & Belle.Connect with Cynthia ThurlowFollow on Twitter, Instagram & LinkedInCheck out Cynthia’s websiteConnect with Kristin RowellOn Facebook, Instagram, and LinkedIn On her website

Today I am delighted to connect with Dr. Bryce Appelbaum! He is a pioneer in neuro-optometry and is passionate about unlocking life’s potential through vision. He is an owner and managing doctor at Appelbaum Vision and practices in the Bethesda and Annapolis, Maryland areas.Our brain uses 48-50% of its physiology just for us to be able to see, and there is a very complex interrelationship between the eyes and the brain.In this episode, Dr. Appelbaum and I dive into his background in neuro-optometry and discuss how his family influenced his career trajectory. We get into eye physiology and the differences between vision and sight and explain how eye problems are also brain problems specific to rewiring our brain and processing. We discuss the impact of nutrition on eye health, foods to support vision and eye health, and how electronics impact myopia. We also talk about ways to address screen limits and visual hygiene, traumatic brain injuries, and more.IN THIS EPISODE YOU WILL LEARN: Dr. Appelbaum explains how his passion for eye and vision health began in the first grade and how he helps people turn their visual weaknesses into strengths. Some of the basics of eye physiology. The interrelationship between our eyes and our brains. Why are more vision problems emerging now than ever before- particularly in the younger generations? What is the difference between eyesight and vision? How do our eyes feed information to the rest of our body? Doing vision therapy versus getting stronger prescription lenses as we age. How vision problems can lead to or be misdiagnosed as ADD, ADHD, or dyslexia.  How does electronic use impact eye health? How to practice 20-20-20 for visual hygiene. Dr. Appelbaum shares some recommendations for managing screen time. The interrelationship between nutrition, metabolic health, and eye health. Some dietary guidelines for the brain injury population. Dr. Appelbaum dives into depth perception. Connect with Cynthia ThurlowFollow on Twitter, Instagram & LinkedInCheck out Cynthia’s websiteConnect with Dr. Bryce AppelbaumOn the Appelbaum Vision website ConcussionClearScreenFit Use code CYNTHIA10On InstagramGo to the College of Optometrists in Vision Development website to find a doctor board-certified in vision therapy close to where you live.

I am honored to have Dr. Stephen Hussey joining me today. He is a chiropractic doctor with an interest in and a methodology related to cardiovascular disease. Dr. Hussey suffered from a large STEMI, a type of myocardial infarction or heart attack, and he has been diabetic since childhood. In this episode, we dive into his background and the open-minded curiosity with which he views the world. We talk about statistics related to cardiovascular disease, mitochondrial dysfunction, the impact of Ancel Keys and his research, how cholesterol and statins work in the body, and the causes of heart attacks. We also discuss ways to navigate cardiovascular health proactively and the impact of fasting.I hope you enjoy listening to our discussion as much as I did recording it! IN THIS EPISODE YOU WILL LEARN: Dr. Hussey shares his background and his journey to figuring out how to manage the various physical conditions he suffered from since childhood. Why Dr. Hussey believes heart disease is not just about diet.  The vast number of Americans currently affected by vascular disorders proves that a different and better treatment approach is required. Dr. Hussey discusses the frustration he experienced trying to navigate conversations with traditionally-trained providers. What may prevent western physicians and practitioners from investigating other effective treatment options? What causes mitochondrial dysfunction? Dr. Hussey explains the metabolic theory of cancer. Why is cancer of the heart so rare? How Ancel Keys profoundly impacted American nutritional guidelines and the health of the American population. The benefits of cholesterol and LDL, and the problem with statins. What causes heart attacks? Dr. Hussey shares his take on meal frequency and snacking and how that relates to heart health. Bio:Dr. Stephen Hussey MS, DC, is a Chiropractor and Functional Medicine practitioner. He attained his Doctorate of Chiropractic and a Master's in Human Nutrition and Functional Medicine from the University of Western States in Portland, OR. He is a health coach, speaker, and the author of two books on health; The Health Evolution: Why Understanding Evolution is the Key to Vibrant Health and Understanding The Heart: Surprising Insights Into The Evolutionary Origins Of Heart Disease - And Why It Matters. Dr. Hussey guides clients from around the world back to health using the latest research and health-attaining strategies. In his downtime, he likes to be outdoors, play sports, read, write, and travel. Connect with Cynthia ThurlowFollow on Twitter, Instagram & LinkedInCheck out Cynthia’s website Connect with Dr. Stephen HusseyOn his websiteOn Facebook, Instagram, Twitter, and LinkedInDr. Hussey’s book, Understanding the Heart, is available from Amazon, Barnes and Noble, and the publisher’s website.

I am excited to connect with one of my favorite neuroscience experts today! Louisa Nicola is at the intersection of neuroscience and athleticism. She helps to bring a fresh understanding of what it takes to achieve peak performance through science-based tools and methods. She is also the host of The Neuro Experience podcast, which focuses on brain health, neuroscience, longevity, and athletics.  Louisa knows how to take complicated subjects related to brain physiology and hormones and explain them so that people can fully understand and appreciate them. In this episode, she and I dive into her background. We discuss her three pillars for peak performance, alcohol, and how sleep impacts the glymphatic system. We get into strategies for better sleep, the perimenopausal brain, how chronobiology impacts sleep, how to address jet lag, and how exercise improves brain performance and health. We also discuss the best foods and supplements for brain health and how creatine enhances performance.  I hope you enjoy listening to today’s conversation as much as I did recording it!  IN THIS EPISODE YOU WILL LEARN: How an accident shifted the trajectory of Louisa’s life.  Louisa unpacks the various stages of sleep and explains why sleep is so important. How sleep impacts the glymphatic system. Some common characteristics of perimenopause. Some simple ways to aid the penetration of naturally secreted hormones into the brain.  How blood pressure fluctuations impact the brain. What is jet lag, and how can we combat it? How does alcohol affect the brain? Louisa explains cardiac remodeling. The value of different types of exercise for brain health. The difference between physical activity and exercise. How our food choices impact our brain health. How to mitigate the effects of traumatic brain injuries. How does creatine monohydrate improve brain performance? Connect with Cynthia Thurlow Follow on X ⁠ ⁠Instagram ⁠ ⁠LinkedIn⁠ Check out Cynthia’s ⁠website⁠  Connect with Louisa Nicola On X and ⁠Instagram⁠  ⁠The Neuro Experience Podcast⁠ Book mentioned ⁠The XX Brain⁠ by Dr. Lisa Mosconi