
JAMAevidence The Rational Clinical Examination
Interviews with authors of Rational Clinical Examination systematic reviews in JAMA about the accuracy of the medical history, physical examination, and laboratory testing for the diagnosis of common medical conditions. JAMAevidence is an evidence-based medicine (EBM) resource created and maintained by JAMA Network to promote the use of EBM to improve patient care.
Latest episodes

14 snips
Aug 4, 2016 • 15min
Understanding How to Use Likelihood Ratios in Clinical Practice: Interview With Dr David L. Simel
Dr. David L. Simel, an expert in likelihood ratios, shares fascinating insights on their vital role in clinical practice. He discusses how likelihood ratios enhance decision-making, particularly in assessing acute coronary syndrome. Simel clarifies the significance of pretest probabilities and challenges traditional diagnostic testing views. He also emphasizes integrating scoring systems like TIMI and HEART to improve risk stratification. By using likelihood ratios effectively, clinicians can better evaluate test results and avoid unnecessary hospital admissions for low-risk patients.

7 snips
Jul 7, 2016 • 18min
Acute Coronary Syndrome: Interview With Dr Alexander C. Fanaroff
Dr. Alexander C. Fanaroff, an expert in Acute Coronary Syndrome, joins the discussion to unravel the complexities of heart conditions. They tackle the often-misinterceived symptoms of heart issues, using real-life patient stories to illustrate misdiagnoses. The conversation dives into the main types of ACS, emphasizing the critical need for awareness and the intricacies of diagnosis. Additionally, they analyze the effectiveness of risk models like TIMI and HEART scores, highlighting the balance between empirical data and clinical intuition in emergency settings.

Apr 7, 2016 • 13min
Does This Older Adult With Lower Extremity Pain Have the Clinical Syndrome of Lumbar Spinal Stenosis?: Interview With Dr Pradeep Suri
Dr David Simel discusses Does This Older Adult With Lower Extremity Pain Have the Clinical Syndrome of Lumbar Spinal Stenosis? with Dr Pradeep Suri.

Mar 3, 2016 • 23min
Does This Patient Have Posttraumatic Stress Disorder? Interview With Dr Michele R. Spoont
Dr Ed Livingston discusses Does This Patient Have Posttraumatic Stress Disorder? with Dr Michele R. Spoont.

Oct 30, 2015 • 30min
Malaria: Interview With Dr Steve M. Taylor
Dr Ed Livingston discusses Malaria with Dr Steve M. Taylor.

Sep 29, 2015 • 33min
Upper Gastrointestinal Bleed: Interview With Dr F. Douglas Srygley and Dr David L. Simel
Dr. F. Douglas Srygley, a gastrointestinal expert, and Dr. David L. Simel, a physician specializing in diagnostics, shed light on the complexities of upper gastrointestinal bleeding. They discuss critical clinical predictors for urgent interventions, emphasizing the significance of patient-reported symptoms. The conversation highlights the limitations of traditional diagnostic tools and the importance of evidence-based practices in enhancing patient outcomes. They also delve into the nuances of diagnostic test performance, offering insights on sensitivity, specificity, and likelihood ratios.

Aug 13, 2015 • 20min
Melanoma: Interview With Dr James M. Grichnik
Dr Ed Livingston discusses Melanoma with Dr James M. Grichnik.

Jul 15, 2015 • 16min
Peripheral Arterial Disease: Interview With Dr Nadia A. Khan
Dr. Ed Livingston discusses Peripheral Arterial Disease with Dr Nadia A. Khan.

Aug 5, 2014 • 12min
Does This Patient Have an Alcohol Problem?: Interview With Dr Sheri A. Keitz
Dr Ed Livingston discusses Does This Patient Have an Alcohol Problem? with Dr Sheri A. Keitz.

Aug 3, 2014 • 7min
Abnormal Central Venous Pressure: Interview With Dr David L. Simel
Joan Stephenson, PhD, discusses Abnormal Central Venous Pressure with Dr David L. Simel.
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