

Dr Karan Explores
OG Podcasts
Join Dr Karan as he meets the world's foremost experts in science and medicine to cut through the BS of modern health advice.
Get my free weekly newsletter filled with easy to action health tips, interesting facts & science to fill your curiosity: https://drkaran.beehiiv.com/subscribe
Get my free weekly newsletter filled with easy to action health tips, interesting facts & science to fill your curiosity: https://drkaran.beehiiv.com/subscribe
Episodes
Mentioned books

Aug 29, 2025 • 57min
Why We Need To Stop Ignoring Men’s Health | George TheTinMen
⚡ Are men’s health issues being ignored? With the rise of the “manosphere”, poor male role models and increasing focus on the harm men cause - one activist argues we’ve begun to see men as the enemy, and it’s costing us.💬 George, known as TheTinMen online, is a men’s health activist. He tackles issues where he feels men are being let down by society - everything from domestic violence to suicide prevention. His view is that men’s physical and mental health is not being taken seriously - and it’s doing them a massive disservice.🎧 Stay tuned to find out:➡︎ Why being a man is the biggest predictor for early death➡︎ Why the term manosphere has become “meaningless”➡ Why the world is lacking good male role models - and where to actually find them➡︎ How 91% of men who died of suicide already saught help first➡︎ Why Adolescence did a bad job of portraying the manosphere📕 Chapters(0:00) Intro(3:12) What is the manosphere?(7:31) Did Netflix’s Adolescence get it right?(9:46) Why the manosphere has exploded(12:06) Why fathers are so important(16:51) Are there any good male role models out there?(24:43) The power dynamic between men and women(27:40) Does men’s health get enough attention?(35:51) Why suicide prevention isn’t working for men(38:54) The issue with Movember - where is the money going?(43:47) Male body image(46:50) How female role models influence men(51:36) Kids watch your every move📱 Connect with me:TikTok: https://www.instagram.com/drkaranrajanYouTube: https://www.youtube.com/@DrKaran Instagram: https://www.tiktok.com/@dr.karanr📱 Connect with TheTinMen:Instagram: https://www.instagram.com/thetinmen/YouTube: https://www.youtube.com/@thetinmenblog 🔥 Get my free weekly newsletter filled with easy to action health tips, interesting facts and science to fill your curiosity: https://drkaran.beehiiv.com/subscribe🔥 For more useful science for your everyday life, grab my best selling book “This Book May Save Your Life”: https://geni.us/DrKaranBook 🎙️ An OG Podcasts production.

Aug 22, 2025 • 50min
How Super-Agers Keep Their Brains Young | Neuroscientist Dr Ben Rein
⚡ If you want a big, healthy and young brain - there is a simple solution that can add years to your life.💬 Neuroscientist Dr Ben Rein explains why social connection, chatting to strangers and seeing your friends is essential for brain health - and can literally make it bigger. He also discusses the brain benefits of pets, the science of empathy and more.🎧 Stay tuned to find out:➡ How pets hijack our brain systems in the best possible way➡︎ How an ‘epidemic of loneliness’ is fueling conditions like dementia and heart disease➡︎ How online interactions and AI chatbots impact brain chemistry➡︎ Where empathy comes from and how to get more of it➡︎ The science of awe and whether free will exists📕 Chapters(0:00) Intro(0:36) Why our brains need friends(2:15) The neuroscience of empathy(5:52) Are pets good for brain health?(10:33) Do animals have empathy too?(12:05) Are WE good for our pets brains?(13:36) Why animals love music(15:28) How ‘super-agers’ keep their brains healthy(20:01) Do virtual chats also help brain health?(22:44) How social connection reduces dementia risk(26:27) What AI chatbots are doing to our brains(30:33) The science of awe and wonder(33:07) How to make your life feel longer(36:44) Empathy and mirror neurons(40:18) Does free will exist?(46:22) How to become more empathetic📱 Connect with me:TikTok: https://www.instagram.com/drkaranrajanYouTube: https://www.youtube.com/@DrKaran Instagram: https://www.tiktok.com/@dr.karanr📱 Connect with Ben:Instagram: https://www.instagram.com/dr.benrein/ YouTube: https://www.youtube.com/c/benrein Website: https://www.benrein.com/ 🔥 Get my free weekly newsletter filled with easy to action health tips, interesting facts and science to fill your curiosity: https://drkaran.beehiiv.com/subscribe🔥 For more useful science for your everyday life, grab my best selling book “This Book May Save Your Life”: https://geni.us/DrKaranBook 🎙️ An OG Podcasts production.

Aug 15, 2025 • 48min
The Simplest Guide To A Healthy Gut | Dr Emily Leeming
⚡ ️Gut health is an absolute minefield. Trying to figure out what works best to protect your gut is becoming increasingly complex - but it doesn’t have to be. The science is pretty clear and in this episode we break down the simplest measures you can take for a healthy gut.💬 Dr Emily Leeming is a gut health dietician and author of Genius Gut. And she’s currently running a very important trial at King’s College London - looking at the link between the gut microbiome and bowel cancer risk. 🎧 Stay tuned to find out:➡ Whether microbiome tests are worth your money (and what to do instead)➡︎ How bowel cancer is on the rise in under 50s (and why fibre is the solution)➡︎ Why you need to spend more time studying your poop➡︎ Whether microplastics are really damaging your gut health➡︎ Where gut health meets neuroscience📕 Chapters(0:00) Intro(0:37) Best way to get on top of your gut health(1:24) Why microbiome tests are a waste of money(10:12) Emily’s KCL study on bowel cancer(20:46) The effect of microplastics on gut health(26:47) Gut factors that are out of your control(32:21) Your gut health starts in your mouth(35:36) Researching non-industralised microbiomes(40:22) How your gut affects your brain📱 Connect with me:TikTok: https://www.instagram.com/drkaranrajanYouTube: https://www.youtube.com/@DrKaran Instagram: https://www.tiktok.com/@dr.karanr📱 Connect with Emily:Instagram: https://www.instagram.com/dremilyleeming/ Website: https://www.emilyleeming.com/ 🔥 Get my free weekly newsletter filled with easy to action health tips, interesting facts and science to fill your curiosity: https://drkaran.beehiiv.com/subscribe🔥 For more useful science for your everyday life, grab my best selling book “This Book May Save Your Life”: https://geni.us/DrKaranBook 🎙️ An OG Podcasts production.

Aug 8, 2025 • 47min
Can Autism and ADHD Be Rewired in Children? | Trenna Sutcliffe
⚡️Autism, ADHD and anxiety are on the rise in children - but there is a way to rewire our kids’ brains and even reverse symptoms of these conditions…if we get in early enough. But how?💬 Trenna Sutcliffe is a developmental-behavioural pediatrician at Sutcliffe Clinic. She helps parents navigate neurodevelopmental conditions and build mentally resilient children. She says the work must start young - and shares key tools and techniques that parents can implement.🎧 Stay tuned to find out:➡ Why ADHD and autism is really on the rise - and how much of it is genetics➡︎ The science of neuroplasticity and why the first 7 years of a child’s life are crucial➡︎ Just how closely linked screentime is to worsening ADHD symptoms➡︎ Why educational spaces simply don’t work for some children➡︎ Why autism is regularly missed in girls📕 Chapters(3:15) Why are ADHD and autism on the rise?(6:48) How much is genetically driven?(9:31) How the environment influences brain health(18:46) Diet & microbiome effects on neurodivergence(22:46) How worried should we be about screentime?(29:05) Why schools aren’t set up right(34:34) What you should do for your kids in their first 7 years(38:48) Why autism is often missed in girls(42:03) Lower rates of autism in ethnic minorities(43:41) Trenna’s top tips for raising healthy kids📱 Connect with me:TikTok: https://www.instagram.com/drkaranrajanYouTube: https://www.youtube.com/@DrKaran Instagram: https://www.tiktok.com/@dr.karanr📱 Connect with Trenna:Website: https://www.sutcliffeclinic.com/trenna-sutcliffe LinkedIn: https://www.linkedin.com/in/trenna-sutcliffe-463001b2/ 🔥 Get my free weekly newsletter filled with easy to action health tips, interesting facts and science to fill your curiosity: https://drkaran.beehiiv.com/subscribe🔥 For more useful science for your everyday life, grab my best selling book “This Book May Save Your Life”: https://geni.us/DrKaranBook 🎙️ An OG Podcasts production.

Aug 1, 2025 • 43min
The NiMe Diet - Eat Like Our Ancestors For Better Gut Health
💬 Jens Walter is a gut health expert at APC Microbiome Ireland, one of the leading microbiome centres in the world - and helped develop the Non-industrialised Microbiome Restore (NiMe) diet.⚡️In this episode, Jens and I discuss how our microbiomes have been shaped throughout human history - and the foods we can eat to make our healthy microbes flourish. 🎧 Stay tuned to find out:➡︎ Just how different our guts are from indigenous communities and our early ancestors➡︎ What the NiMe diet is and how it can supercharge your gut health➡︎ Why community and culture is just as important as food for gut health➡︎ Why some of our gut microbes have gone extinct➡︎ How pairing meat with the right kind of fibre can increase its benefits📕 Chapters(00:43) How industrialisation has changed our microbiome(02:18) Do personalised diets work for gut health?(05:52) Emerging gut microbe research(07:27) How sharing microbes in communities improves gut health(12:56) Combining the benefits of Western and indigenous lifestyles(15:01) How different our guts are from ancient humans(18:15) Can we regain extinct microbes?(21:35) Exploring the Yanomami tribe(24:11) The NiMe diet(27:14) Should we cut out all dairy?(30:01) Balance vs restriction(32:23) Benefits of pairing fibre with meat(35:27) Best resistant starches to eat(38:36) Ancient vegetables: Are they better for us?📱 Connect with me:Instagram: https://www.instagram.com/drkaranrajanYouTube: https://www.youtube.com/@DrKaran TikTok: https://www.tiktok.com/@dr.karanr📱 Connect with Jens Walter:LinkedIn: https://www.linkedin.com/in/jens-walter-b1a1127a/🔥 Get my free weekly newsletter filled with easy to action health tips, interesting facts and science to fill your curiosity: https://drkaran.beehiiv.com/subscribe🔥 For more useful science for your everyday life, grab my best selling book “This Book May Save Your Life”: https://geni.us/DrKaranBook 🎙️ An OG Podcasts production.

Jul 25, 2025 • 52min
Ozempic Is Just the Beginning: What’s Next in Weight Loss Drugs | Dr Spencer Nadolsky
💬 Dr Spencer Nadolsky is an obesity and lipid specialist, and an expert in GLP-1 care. He’s also the co-host of the Docs Who Lift podcast.⚡️In this episode Spencer and I discuss emerging research around weight loss injections tirzepatide and semaglutide, known as Ozempic, Wegovy and Mounjaro - and discuss the proper use of these drugs.🎧 Stay tuned to find out:➡︎ Why old restrictions on weight loss drugs are no longer being enforced➡ How a combo of GLP-1 and GIP may be even more revolutionary for weight loss➡︎ Why most people have to take these drugs for life➡︎ Why people get so angry when people lose weight on GLP-1s➡︎ How GLP-1 drugs are going to make weight-loss surgery extinct📕 Chapters(0:41) The non-weight loss benefits from GLP-1 use(4:55) Getting the dosage right(7:24) Drugs of the future(11:09) How to get started on a weight-loss injection(16:38) Why restrictions on weight loss drugs are being lifted(19:46) Why people get mad about GLP-1 use(23:57) Do you have to take these drugs for life?(27:55) Do fat cells have memory?(29:25) What if you want to stop GLP-1 use?(31:48) The mental health drawbacks of weight loss drugs(35:44) Unique insights from Spencer’s time with patients(38:47) Is excessive muscle loss really a big problem?(42:46) Should everyone be taking GLP-1s?(45:14) Will weight loss surgeries go extinct?(49:11) GLP supplements are a scam📱 Connect with me:TikTok: https://www.instagram.com/drkaranrajanYouTube: https://www.youtube.com/@DrKaran Instagram: https://www.tiktok.com/@dr.karanr📱 Connect with Spencer:Instagram: https://www.instagram.com/drnadolsky/ X: https://x.com/DrNadolsky 🔥 Get my free weekly newsletter filled with easy to action health tips, interesting facts and science to fill your curiosity: https://drkaran.beehiiv.com/subscribe🔥 For more useful science for your everyday life, grab my best selling book “This Book May Save Your Life”: https://geni.us/DrKaranBook 🎙️ An OG Podcasts production.

Jul 18, 2025 • 52min
It Only Takes 3 Months to Supercharge Fertility - Here’s How | Ro Huntriss
💬 Ro Huntriss is a world-leading fertility expert, recently crowned ‘Best Fertility Dietitian’ by The European Fertility Society. She has extensive experience in women’s health and is also the author of Deliciously Healthy Fertility.⚡️In this episode Ro and I discuss the incredible power we have to influence our own ability to conceive (for both women and men) and improve the health outcomes of our children - simply by focusing on the food we eat.🎧 Stay tuned to find out:➡ Fertility friendly foods - and what to avoid for better conception➡︎ What DNA fragmentation has to do with male fertility and sperm quality➡︎ About the rise of ‘Ozempic babies’ and how GLP-1 agonists impact fertility➡︎ The evolving role of microbiome research in fertility➡︎ Which supplements actually work📕 Chapters(0:41) Fertility award winner(1:51) How men are involved in fertility(4:44) Why is infertility so common?(6:34) Fertility friendly foods(8:18) Dietary reasons for low fertility(10:09) Fertility and the microbiome(18:14) Supplements for fertility(24:14) Testing your fertility(28:43) How your diet improves your child’s long-term health(30:36) Advice for chronic conditions like endometriosis(35:52) Ozempic babies(40:29) Dr Karan’s Ozempic prediction(42:38) What you should STOP doing for fertility(45:24) Diet impact on pregnancy related complications(47:00) Improving fertility can be simple📱 Connect with me:TikTok: https://www.instagram.com/drkaranrajanYouTube: https://www.youtube.com/@DrKaran Instagram: https://www.tiktok.com/@dr.karanr📱 Connect with Ro:Instagram: https://www.instagram.com/fertility.dietitian.uk/Website: https://dietitianro.co.uk/ 🔥 Get my free weekly newsletter filled with easy to action health tips, interesting facts and science to fill your curiosity: https://drkaran.beehiiv.com/subscribe🔥 For more useful science for your everyday life, grab my best selling book “This Book May Save Your Life”: https://geni.us/DrKaranBook 🎙️ An OG Podcasts production.

Jul 11, 2025 • 42min
Want Better Skin, Sleep & Energy? Start With Your Gut | Megan Rossi
💬 Dr Megan Rossi, aka The Gut Health Doctor, is an award‑winning dietitian and nutritionist with a PhD in gut microbiome science. She's the founder of The Gut Health Clinic and the Bio&Me food brand. She’s also a Sunday Times bestselling author, dedicated to translating cutting-edge gut research into practical, real‑world health advice.⚡️In this episode, Megan and I dive into the science of gut health, exploring how your gut influences everything from mood and immunity to skin and sleep… and what you can do to improve it.🎧 Stay tuned to find out:➡︎ How your gut health impacts your mood, energy, skin, and overall wellbeing➡︎ Why you need to eat 30 different plant-based foods per week➡︎ Which fermented foods can naturally boost gut health➡︎ The gut effects of artificial sweeteners and ultra-processed foods➡︎ How stress, sleep, and movement affect gut health📕 Chapters(00:50) What’s so special about gut health?(02:38) Don’t assume you’ve got a healthy gut(04:42) Quickfire questions(06:17) The importance of gut health(09:16) Good bugs versus bad bugs(12:06) Diversity is good for the gut(14:23) The Super Six(17:15) Should you restrict dairy?(19:39) Probiotic foods and lactose intolerance(23:05) Causes of bloating(28:32) Fermented food benefits(31:44) What’s the difference between probiotic supplements and fermented foods?(35:22) Why fermented foods aren’t the answer for specific conditions(37:26) Understanding the power of probiotics(38:56) Can you trust off-the-shelf probiotics?📱 Connect with me:Instagram: https://www.instagram.com/drkaranrajanYouTube: https://www.youtube.com/@DrKaran TikTok: https://www.tiktok.com/@dr.karanr📱 Connect with Dr Megan Rossi:Instagram: https://www.instagram.com/theguthealthdoctorTikTok: https://www.tiktok.com/@theguthealthdoctor🔥 Get my free weekly newsletter filled with easy to action health tips, interesting facts and science to fill your curiosity: https://drkaran.beehiiv.com/subscribe🔥 For more useful science for your everyday life, grab my best selling book “This Book May Save Your Life”: https://geni.us/DrKaranBook 🎙️ An OG Podcasts production.

Jul 4, 2025 • 53min
I Got Deepfaked - AI Misinformation Is SCARY Right Now | Alex Ruani
💬 Alex Ruani is a doctoral researcher in diet-health misinformation at University College London. She studies how misinformation spreads, the potential harm it can do - and what techniques we should be using to stop it.⚡️In this episode Alex and I discuss the rising influence of technology and artificial intelligence on fake news and the spreading of misinformation - including how I’ve recently become the victim of a deepfake scam.🎧 Stay tuned to find out:➡︎ Why social media platforms say misinformation is a “necessary weed”➡ How misinformation online is leading to real life deaths➡︎ How AI is getting so good at spreading misinformation - threatening democracy➡︎ How one company used a Deepfake clone of ME to sell their supplements➡︎ Why the CapCut issue opens up massive trust issues with tech companies📕 Chapters(0:58) How bad is misinformation right now?(4:38) How easy it is to avoid spreading fake news(7:19) Is misinformation research working?(12:16) Why social media platforms don’t want to tackle misinformation(17:14) How to avoid restricting free speech(22:12) How I got Deepfaked(32:24) The CapCut problem: Why you should read Ts&Cs(40:47) We’re using ChatGPT wrong(46:16) How AI is rotting your brain📱 Connect with me:TikTok: https://www.instagram.com/drkaranrajanYouTube: https://www.youtube.com/@DrKaran Instagram: https://www.tiktok.com/@dr.karanr📱 Connect with Alex:Instagram: https://www.instagram.com/alexruani/ LinkedIn: https://www.linkedin.com/in/alejandraruani/ 🔥 Get my free weekly newsletter filled with easy to action health tips, interesting facts and science to fill your curiosity: https://drkaran.beehiiv.com/subscribe🔥 For more useful science for your everyday life, grab my best selling book “This Book May Save Your Life”: https://geni.us/DrKaranBook 🎙️ An OG Podcasts production.

Jun 27, 2025 • 48min
What Makes Us Fat? The Genetics of Appetite | Giles Yeo
💬 Dr. Giles Yeo is a geneticist and obesity researcher at the University of Cambridge. He specialises in how brain and genetic factors influence appetite and body weight regulation. He’s known for communicating complex science around obesity, appetite, and nutrition in an accessible way through media, books, and public talks.⚡️In this episode, Giles and I dig into how our genes - especially those in the brain’s appetite and reward centres - shape our hunger signals, fat storage, and body fat “set‑points”. We explain why diets often fail and how to reset our appetite.🎧 Stay tuned to find out:➡︎ Just how strongly our genes are to blame for appetite and body weight➡︎ The specific brain region that regulates hunger and energy balance➡︎ Whether weight loss injections are really the answer➡︎ Why obesity is biological - not a moral failing➡︎ The 3 numbers to remember for weight loss📕 Chapters(00:47) Welcome back(01:01) The genetic reason for obesity(02:49) The role of the brain in weight gain(05:15) Reward, hunger and fullness(08:14) How fat cells influence how hungry you are(10:09) The hypothalamus map(13:19) What to do when your meal’s not enough(16:16) Why hormones don’t limit your appetite(18:21) The paradox of leptin resistance(20:55) Insulin resistance and weight gain(22:30) Defining high quality weight loss(24:56) The yo-yo effect(26:13) Why weight loss drugs aren’t enough(30:17) The wider benefits of GLP-1 agonist weight loss drugs(34:19) Gene mutation and obesity(37:43) Gut hormones and the role they play(41:06) The effect of early years education(44:30) Three numbers to remember(46:23) Your DNA isn’t your destiny📱 Connect with me:Instagram: https://www.instagram.com/drkaranrajanYouTube: https://www.youtube.com/@DrKaran TikTok: https://www.tiktok.com/@dr.karanr📱 Connect with Dr Giles Yeo:Instagram: https://www.instagram.com/gilesyeoX: https://x.com/GilesYeo 📕 Grab Giles’ book here: https://amzn.eu/d/hoAnVLr 🔥 Get my free weekly newsletter filled with easy to action health tips, interesting facts and science to fill your curiosity: https://drkaran.beehiiv.com/subscribe🔥 For more useful science for your everyday life, grab my best selling book “This Book May Save Your Life”: https://geni.us/DrKaranBook 🎙️ An OG Podcasts production.