The Carlat Psychiatry Podcast

The discussion centers around the MTHFR gene and its variants, which play a crucial role in mental health, particularly in depression. Testing for MTHFR's impact on treatment with methylfolate is analyzed, revealing important links to clinical outcomes. The effectiveness of SAMe as a depression treatment is evaluated, showcasing mixed trial results. Additionally, the podcast emphasizes the significance of folate and its affordable options, highlighting its historical importance and benefits in mental health treatment. It's a fascinating dive into genetics and psychiatry!

We learn how psychiatrists figured out that low folate causes depression, and how the vitamin can treat depression even when serum levels are normal.CME: Take the CME Post-Test for this EpisodePublished On: 04/28/2025Duration: 08 minutes, 29 secondsChris Aiken, MD, and Kellie Newsome, PMHNP have disclosed no relevant financial or other interests in any commercial companies pertaining to this educational activity.

We interview Victor Hoffbrand on the discovery of folate and look at how this vitamin can help or harm the action of anticonvulsants in bipolar disorder.CME: Take the CME Post-Test for this EpisodePublished On: 04/21/2025Duration: 16 minutes, 40 secondsChris Aiken, MD, and Kellie Newsome, PMHNP have disclosed no relevant financial or other interests in any commercial companies pertaining to this educational activity.

1 in 3 Americans were victims of online scams in the past year. Even when you know your patient is being scammed, it is hard to pull them out. We speak with Cathy Wilson about the therapeutic techniques to break psychological trap.CME: Take the CME Post-Test for this EpisodePublished On: 04/14/2025Duration: 11 minutes, 27 secondsChris Aiken, MD, Cathy Wilson, LPC, ACS, and Kellie Newsome, PMHNP have disclosed no relevant financial or other interests in any commercial companies pertaining to this educational activity.

1 in 3 Americans were victims of online scams in the past year. Learn the signs, and the psychological traps that can make people lose everything.How to help patients build fulfilling lives even in the face of unremitted illness.CME: Take the CME Post-Test for this EpisodePublished On: 04/07/2025Duration: 13 minutes, 13 secondsChris Aiken, MD, Cathy Wilson, LPC, ACS, and Kellie Newsome, PMHNP have disclosed no relevant financial or other interests in any commercial companies pertaining to this educational activity.

The Fentanyl overdose crisis is now one of the leading causes of death among adolescents, and it is happening in every corner of the country. Stay with us as we talk about the state of the crisis and the steps we can take to save lives.CME: Take the CME Post-Test for this EpisodePublished On: 03/31/2025Duration: 15 minutes, 41 secondsJoshua Feder, MD, and Mara Goverman, LCSW, have disclosed no relevant financial or other interests in any commercial companies pertaining to this educational activity.

Dive into the intriguing effects of social media on youth mental health, balancing connection with hazards like misinformation and cyberbullying. Discover how online interactions shape plural identities and impact clinical practices, emphasizing holistic therapeutic approaches. Explore the complexities of teen sexting, recognizing its relationship-building benefits alongside serious risks. Lastly, understand cyberbullying's profound implications on mental well-being and the crucial need for open dialogue between teens and adults.

Margaret Chislom, a Professor of Psychiatry at Johns Hopkins University, discusses how individuals with mental illness can still flourish in life. She emphasizes the importance of relationships and engaging activities, sharing success stories of patients overcoming challenges. The conversation unveils four pathways to flourishing: family, community, work, and education. Chislom advocates for a holistic approach, valuing connections and nature in recovery, and redefines education as a means for personal growth while addressing isolation during the pandemic.

Postpartum depression affects one in eight mothers, making early intervention crucial for both maternal and infant health. The hosts discuss traditional treatments and the promising newcomer, xerenolone, known for its quick effects. They explore rapid-acting depression medications and highlight the importance of holistic recovery, incorporating therapy and support. Additionally, they differentiate between severe postpartum depression and psychosis, cautioning about medical factors that heighten risks, particularly in women with bipolar disorder.

The discussion dives into the critical timing for interventions related to weight gain from antipsychotics and managing panic attacks. It clarifies the difference between panic attacks and panic disorder, emphasizing a reframed perspective on panic. Cognitive behavioral therapy emerges as a key treatment, supported by alternative methods like aerobic exercise and mindfulness. The podcast also highlights metformin's role in mitigating weight gain in psychiatric patients and discusses the latest advancements in psychiatric medications.