

AI + a16z
a16z
Artificial intelligence is changing everything from art to enterprise IT, and a16z is watching all of it with a close eye. This podcast features discussions with leading AI engineers, founders, and experts, as well as our general partners, about where the technology and industry are heading.
Episodes
Mentioned books

23 snips
Jan 23, 2026 • 45min
How Mintlify Is Rebuilding Documentation for Coding Agents
Hahnbee Lee, Mintlify cofounder focused on product intuition and developer experience, and Han Wang, Mintlify cofounder building AI-powered documentation platforms. They discuss how coding agents reshape what documentation must be, Mintlify’s many pivots and hands-on customer wins, turning docs into infrastructure for agents and internal knowledge, and practical tradeoffs for self-healing, machine-readable docs.

38 snips
Jan 22, 2026 • 44min
Inferact: Building the Infrastructure That Runs Modern AI
Simon Mo and Woosuk Kwon, co-founders of Infraact and core maintainers of the vLLM inference engine, dive into the complexities of modern AI infrastructure. They discuss how vLLM originated from Berkeley research to enhance large language model deployment. The duo highlights the challenges of scheduling and managing diverse model architectures for efficient inference. They also share their vision for a universal inference layer that supports any hardware or model, emphasizing the importance of open-source collaboration for innovation.

8 snips
Jan 20, 2026 • 47min
How Should AI Be Regulated? Use vs. Development
Martin Casado, a general partner at a16z and a former CTO of Nicira, shares his insights on AI regulation. He emphasizes the importance of focusing on how AI is used rather than how it's developed, drawing parallels with past tech shifts. Casado warns that existing laws should apply when AI is used for wrongdoing. He highlights the risks of hasty regulations and the need for evidence-based policies. The discussion touches on the significance of open-source AI for U.S. competitiveness and stresses learning from historical tech governance to create effective regulations.

139 snips
Jan 13, 2026 • 28min
Michael Truell: How Cursor Builds at the Speed of AI
In this enlightening conversation, Michael Truell, CEO of Cursor, a cutting-edge developer tool company he co-founded with MIT colleagues, shares insights on navigating the rapid growth of AI-powered coding tools. They discuss the strategic decision to focus on power users rather than broad accessibility, and how their unique hiring process, featuring two-day trials, fosters a strong company culture. Michael also reveals the benefits of owning the entire code editor while managing scaling challenges and considers the philosophical implications of building tools that could one day disrupt their own business.

186 snips
Jan 6, 2026 • 1h 40min
Dylan Patel on the AI Chip Race - NVIDIA, Intel & the US Government
Dylan Patel, chief analyst at SemiAnalysis, dives into the monumental $5 billion investment by Nvidia in Intel, shaking up the semiconductor landscape. He discusses the implications for tech giants like AMD, ARM, and Huawei in the evolving AI chip race. Key topics include the challenges faced by China's chip industry and Nvidia's strategic positioning under Jensen Huang's leadership. The conversation also highlights how Nvidia's rapid execution and bold investments are setting the stage for future growth in AI infrastructure and cloud services.

53 snips
Dec 30, 2025 • 1h 22min
Feed Drop from The Generalist: Why a16z's Martin Casado believes the AI boom still has years to run
In a conversation with Mario Gabriele, Martin Casado, a General Partner at Andreessen Horowitz, discusses why he believes the AI boom is still in its early stages and likens the current excitement to the late-90s dot-com era. He outlines the potential for AI coding to become a multi-trillion-dollar market and emphasizes the importance of market-first investing. Martin also highlights challenges in enterprise AI adoption and the growing impact of open-source models, while urging the U.S. to enhance policies to foster innovation.

43 snips
Dec 23, 2025 • 23min
Fei-Fei Li: World Models and the Multiverse
Fei-Fei Li, cofounder and CEO of World Labs, is a visionary in computer vision and AI. In this discussion, she reveals the crucial role of spatial intelligence in AI, explaining why world models can transform robotics and creativity. Reflecting on her journey, she describes the unique partnership with early investor Martin Casado. They delve into the limitations of language models versus the necessity of 3D understanding, and explore exciting applications for world models, paving the way for multiverse experiences in both real and virtual realms.

72 snips
Dec 16, 2025 • 39min
Building the “See Something, Say Something” AI for Every Camera
Shikhar Shrestha, CEO and cofounder of Ambient, discusses how a childhood trauma pushed him to revolutionize security with AI. He shares how Ambient's technology empowers cameras to detect and prevent threats in real-time. Shikhar explains the development of their unique reasoning vision-language model, Pulsar, and how it efficiently analyzes footage while respecting privacy. The conversation touches on real-world incidents that Ambient has averted, the challenges of operating during COVID, and the critical need for an AI-driven future in physical security.

85 snips
Dec 10, 2025 • 39min
The AI That Found A Bug In The World’s Most Audited Code
Matt Knight, OpenAI's VP of Security Products and Research, shares his insights on Aardvark, an AI agent revolutionizing security by discovering vulnerabilities like a human. He discusses the evolution from GPT-3's limitations to GPT-4's breakthroughs in log analysis and cybercrime chat decoding. Aardvark's ability to automate threat modeling, validate exploits, and generate patches promises to ease the cybersecurity labor shortage and empower open source maintainers. Knight emphasizes AI's role in augmenting human analysts, not replacing them.

214 snips
Dec 5, 2025 • 1h 23min
The Death of Data Gatekeeping: AI Makes Everyone An Analyst | Hex Cofounder
Barry McCardel, Co-founder and CEO of Hex, shares insights on how AI is transforming data analysis. He reveals the limitations of traditional dashboards and advocates for democratizing data access through conversational interfaces like Threads. Barry discusses how AI can lower barriers for users to explore data and anticipates insights proactively. He emphasizes the importance of context in analytics and describes Hex’s approach to integrating AI into every aspect of their product development, moving away from standalone AI teams.


